MMP13 Antikörper (C-Term)

Produktnummer ABIN5534535

Produktdetails anti-MMP13 Antikörper

Target: MMP13 (Matrix Metallopeptidase 13 (Collagenase 3) (MMP13))

Bindungsspezifität: AA 295-324, C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MMP13 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Immunogen: This MMP13 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 295-324 amino acids from the C-terminal region of human MMP13.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: For WB starting dilution is: 1:500

For IHC-P starting dilution is: 1:50~100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 2 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu MMP13

Target: MMP13 (Matrix Metallopeptidase 13 (Collagenase 3) (MMP13))

Andere Bezeichnung: MMP13 (MMP13 Produkte)

Synonyme: CLG3 antikoerper, MANDP1 antikoerper, Clg antikoerper, MMP-13 antikoerper, Mmp1 antikoerper, cb1034 antikoerper, mmp13 antikoerper, gene A antikoerper, xCol antikoerper, xcl3 antikoerper, MMP13 antikoerper, MGC108008 antikoerper, matrix metallopeptidase 13 antikoerper, matrix metallopeptidase 13a antikoerper, matrix metallopeptidase 13 (collagenase 3) like S homeolog antikoerper, matrix metallopeptidase 13 (collagenase 3) antikoerper, matrix metalloproteinase 13 antikoerper, matrix metallopeptidase 13 (collagenase 3) like L homeolog antikoerper, MMP13 antikoerper, Mmp13 antikoerper, mmp13a antikoerper, mmp13l.S antikoerper, mmp13 antikoerper, LOC100136348 antikoerper, mmp13l.L antikoerper

Hintergrund: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development,reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The protein encoded by this gene cleaves type II collagen more efficiently than types I and III. It may be involved in articular cartilage turnover and cartilage pathophysiology associated with osteoarthritis. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.

Molekulargewicht: 54 kDa

Gen-ID: 4322

UniProt: P45452