PTPN22 Antikörper (C-Term)

Produktnummer ABIN5534474

Produktdetails anti-PTPN22 Antikörper

Target: PTPN22 (Tyrosine-Protein Phosphatase Non-Receptor Type 22 (PTPN22))

Bindungsspezifität: AA 663-691, C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PTPN22 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This PTPN22 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 663-691 amino acids from the C-terminal region of human PTPN22.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: For WB starting dilution is: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu PTPN22

Target: PTPN22 (Tyrosine-Protein Phosphatase Non-Receptor Type 22 (PTPN22))

Andere Bezeichnung: PTPN22 (PTPN22 Produkte)

Synonyme: 70zpep antikoerper, PEP antikoerper, Ptpn8 antikoerper, LYP antikoerper, LYP1 antikoerper, LYP2 antikoerper, PTPN8 antikoerper, protein tyrosine phosphatase, non-receptor type 22 (lymphoid) antikoerper, protein tyrosine phosphatase, non-receptor type 22 antikoerper, Ptpn22 antikoerper, PTPN22 antikoerper

Hintergrund: This gene encodes of member of the non-receptor class 4 subfamily of the protein-tyrosine phosphatase family. The encoded protein is a lymphoid-specific intracellular phosphatase that associates with the molecular adapter protein CBL and may be involved in regulating CBL function in the T-cell receptor signaling pathway. Mutations in this gene may be associated with a range of autoimmune disorders including Type 1 Diabetes, rheumatoid arthritis, systemic lupus erythematosus and Graves' disease. Alternatively spliced transcript variants encoding distinct isoforms have been described.

Molekulargewicht: 92 kDa

Gen-ID: 26191

UniProt: Q9Y2R2