ARHGEF6 Antikörper (C-Term)

Produktnummer ABIN5533583

Produktdetails anti-ARHGEF6 Antikörper

Target: ARHGEF6 (rho Guanine Nucleotide Exchange Factor (GEF) 6 (ARHGEF6))

Bindungsspezifität: AA 614-641, C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ARHGEF6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This ARHGEF6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 614-641 amino acids from the C-terminal region of human ARHGEF6.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: For WB starting dilution is: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu ARHGEF6

Target: ARHGEF6 (rho Guanine Nucleotide Exchange Factor (GEF) 6 (ARHGEF6))

Andere Bezeichnung: ARHGEF6 (ARHGEF6 Produkte)

Synonyme: COOL2 antikoerper, Cool-2 antikoerper, MRX46 antikoerper, PIXA antikoerper, alpha-PIX antikoerper, alphaPIX antikoerper, 1600028C08Rik antikoerper, 1700038J06Rik antikoerper, 4930592P22Rik antikoerper, Rac/Cdc42 guanine nucleotide exchange factor 6 antikoerper, Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 antikoerper, ARHGEF6 antikoerper, Arhgef6 antikoerper

Hintergrund: Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein belongs to a family of cytoplasmic proteins that activate the Ras-like family of Rho proteins by exchanging bound GDP for GTP. It may form a complex with G proteins and stimulate Rho-dependent signals. This protein is activated by PI3-kinase. Mutations in this gene can cause X-chromosomal non-specific mental retardation. [provided by RefSeq].

Molekulargewicht: 87 kDa

Gen-ID: 9459

UniProt: Q15052

Pathways: Neurotrophin Signalübertragung