PRMT5 Antikörper (C-Term)

Produktnummer ABIN5533307

Produktdetails anti-PRMT5 Antikörper

Target: PRMT5 (Protein Arginine Methyltransferase 5 (PRMT5))

Bindungsspezifität: AA 473-499, C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PRMT5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Immunogen: This PRMT5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 473-499 amino acids from the C-terminal region of human PRMT5.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: For WB starting dilution is: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 2 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu PRMT5

Target: PRMT5 (Protein Arginine Methyltransferase 5 (PRMT5))

Andere Bezeichnung: PRMT5 (PRMT5 Produkte)

Synonyme: HRMT1L5 antikoerper, IBP72 antikoerper, JBP1 antikoerper, SKB1 antikoerper, SKB1Hs antikoerper, Jbp1 antikoerper, Skb1 antikoerper, si:zc14a17.2 antikoerper, skb1 antikoerper, wu:fb95f10 antikoerper, zgc:110669 antikoerper, hsl7 antikoerper, DDBDRAFT_0187422 antikoerper, DDBDRAFT_0235403 antikoerper, DDB_0187422 antikoerper, DDB_0235403 antikoerper, NV18830 antikoerper, jbp1 antikoerper, ibp72 antikoerper, skb1hs antikoerper, hrmt1l5 antikoerper, protein arginine methyltransferase 5 antikoerper, protein arginine N-methyltransferase 5 antikoerper, protein arginine methyltransferase 5 L homeolog antikoerper, putative arginine N-methyltransferase, type II antikoerper, Skb1 family protein antikoerper, Protein arginine N-methyltransferase 5 antikoerper, PRMT5 antikoerper, Prmt5 antikoerper, prmt5 antikoerper, prmt5.L antikoerper, LOC100115766 antikoerper, prmt-5 antikoerper

Hintergrund: Arginine methylation is an irreversible post translational modification which has only recently been linked to protein activity. At least three types of PRMT enzymes have been identified in mammalian cells. These enzymes have been shown to have essential regulatory functions by methylation of key proteins in several fundamental areas. These protein include nuclear proteins, IL enhancer binding factor, nuclear factors, cell cycle proteins, signal transduction proteins, apoptosis proteins, and viral proteins. The mammalian PRMT family currently consists of 7 members that share two large domains of homology. Outside of these domains, epitopes were identified and antibodies against all 7 PRMT members have been developed.

Molekulargewicht: 73 kDa

Gen-ID: 10419

UniProt: O14744

Pathways: Chromatin Binding, Regulation of Muscle Cell Differentiation, Ribonucleoprotein Complex Subunit Organization, Skeletal Muscle Fiber Development