Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Aufreinigung
This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This TARBP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 60-89 amino acids from the N-terminal region of human TARBP2.
TARBP2
Reaktivität: Human, Maus
WB, IF
Wirt: Kaninchen
Polyclonal
unconjugated
Applikationshinweise
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
0.5 mg/mL
Buffer
Supplied in PBS with 0.09 % (W/V) sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C
Informationen zur Lagerung
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Target
TARBP2
(TAR (HIV-1) RNA Binding Protein 2 (TARBP2))
trbp antikoerper, trbp1 antikoerper, trbp2 antikoerper, MGC97783 antikoerper, TARBP2 antikoerper, LOQS antikoerper, TRBP antikoerper, TRBP1 antikoerper, TRBP2 antikoerper, fj51e12 antikoerper, wu:fj51e12 antikoerper, zgc:63778 antikoerper, Prbp antikoerper, TAR (HIV-1) RNA binding protein 2 antikoerper, TARBP2, RISC loading complex RNA binding subunit antikoerper, TAR (HIV-1) RNA binding protein 2 L homeolog antikoerper, TAR (HIV) RNA binding protein 2 antikoerper, tarbp2 antikoerper, TARBP2 antikoerper, tarbp2.L antikoerper, Tarbp2 antikoerper
Hintergrund
HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene binds between the bulge and the loop of the HIV-1 TAR RNA regulatory element and activates HIV-1 gene expression in synergy with the viral Tat protein. Alternative splicing results in multiple transcript variants encoding different isoforms. This gene also has a pseudogene.