ARHGDIB Antikörper (C-Term)

Produktnummer ABIN5532793

Produktdetails anti-ARHGDIB Antikörper

Target: ARHGDIB (rho GDP Dissociation Inhibitor (GDI) beta (ARHGDIB))

Bindungsspezifität: AA 160-188, C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ARHGDIB Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This ARHGDIB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 160-188 amino acids from the C-terminal region of human ARHGDIB.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu ARHGDIB

Target: ARHGDIB (rho GDP Dissociation Inhibitor (GDI) beta (ARHGDIB))

Andere Bezeichnung: ARHGDIB (ARHGDIB Produkte)

Synonyme: ARHGDIB antikoerper, zgc:65966 antikoerper, arhgdib antikoerper, MGC69067 antikoerper, gdia2 antikoerper, rhodgi-2 antikoerper, rhodgi2 antikoerper, D4 antikoerper, GDIA2 antikoerper, GDID4 antikoerper, LYGDI antikoerper, Ly-GDI antikoerper, RAP1GN1 antikoerper, RhoGDI2 antikoerper, Gdid4 antikoerper, Rho GDP dissociation inhibitor (GDI) gamma antikoerper, Rho GDP dissociation inhibitor (GDI) beta S homeolog antikoerper, Rho GDP dissociation inhibitor beta antikoerper, Rho GDP dissociation inhibitor (GDI) beta antikoerper, Rho, GDP dissociation inhibitor (GDI) beta antikoerper, arhgdig antikoerper, arhgdib.S antikoerper, ARHGDIB antikoerper, arhgdib antikoerper, Arhgdib antikoerper

Hintergrund: Members of the Rho (or ARH) protein family (see MIM 165390) and other Ras-related small GTP-binding proteins (see MIM 179520) are involved in diverse cellular events, including cell signaling, proliferation, cytoskeletal organization, and secretion. The GTP-binding proteins are active only in the GTP-bound state. At least 3 classes of proteins tightly regulate cycling between the GTP-bound and GDP-bound states: GTPase-activating proteins (GAPs), guanine nucleotide-releasing factors (GRFs), and GDP-dissociation inhibitors (GDIs). The GDIs, including ARHGDIB, decrease the rate of GDP dissociation from Ras-like GTPases (summary by Scherle et al., 1993 [PubMed 8356058]).

Molekulargewicht: 23 kDa

Gen-ID: 397

UniProt: P52566

Pathways: Caspase Kaskade in der Apoptose