This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This ARAP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 63-93 amino acids from the N-terminal region of human ARAP2.
ARAP2
Reaktivität: Human
WB, ELISA
Wirt: Kaninchen
Polyclonal
PE
Applikationshinweise
For WB starting dilution is: 1:1000
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
0.5 mg/mL
Buffer
Supplied in PBS with 0.09 % (W/V) sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C
Informationen zur Lagerung
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Target
ARAP2
(ArfGAP with RhoGAP Domain, Ankyrin Repeat and PH Domain 2 (ARAP2))
CENTD1 antikoerper, PARX antikoerper, Centd1 antikoerper, Gm148 antikoerper, mKIAA0580 antikoerper, ARAP2 antikoerper, ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 antikoerper, arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 2 antikoerper, ARAP2 antikoerper, Arap2 antikoerper, LOC100567363 antikoerper
Hintergrund
The protein encoded by this gene contains ARF-GAP, RHO-GAP, ankyrin repeat, RAS-associating, and pleckstrin homology domains. The protein is a phosphatidylinositol (3,4,5)-trisphosphate-dependent Arf6 GAP that binds RhoA-GTP, but it lacks the predicted catalytic arginine in the RHO-GAP domain and does not have RHO-GAP activity. The protein associates with focal adhesions and functions downstream of RhoA to regulate focal adhesion dynamics.