This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This ABCD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 257-285 amino acids from the Central region of human ABCD1.
ABCD1
Reaktivität: Human
WB
Wirt: Kaninchen
Polyclonal
unconjugated
Applikationshinweise
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:50~100
For FACS starting dilution is: 1:10~50
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
0.32 mg/mL
Buffer
Supplied in PBS with 0.09 % (W/V) sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C
Informationen zur Lagerung
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Target
ABCD1
(ATP-Binding Cassette, Sub-Family D (Ald), Member 1 (ABCD1))
ABC42 antikoerper, ALD antikoerper, ALDP antikoerper, AMN antikoerper, RGD1562128 antikoerper, zgc:172102 antikoerper, ABCD1 antikoerper, Ald antikoerper, Aldgh antikoerper, ATP binding cassette subfamily D member 1 antikoerper, ATP-binding cassette, sub-family D (ALD), member 1 antikoerper, ATP-binding cassette sub-family D member 1 antikoerper, ATP binding cassette subfamily D member 1 L homeolog antikoerper, ABCD1 antikoerper, Abcd1 antikoerper, abcd1 antikoerper, CpipJ_CPIJ013253 antikoerper, VDBG_05717 antikoerper, abcd1.L antikoerper
Hintergrund
ABCD1 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. This peroxisomal membrane protein is likely involved in the peroxisomal transport or catabolism of very long chain fatty acids. Defects in this gene have been identified as the underlying cause of adrenoleukodystrophy, an X-chromosome recessively inherited demyelinating disorder of the nervous system.