TRIB1 Antikörper (C-Term)

Produktnummer ABIN5532742

Produktdetails anti-TRIB1 Antikörper

Target: TRIB1 (Tribbles Homolog 1 (TRIB1))

Bindungsspezifität: AA 341-370, C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TRIB1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Immunogen: This TRIB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 341-370 amino acids from the C-terminal region of human TRIB1.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: For WB starting dilution is: 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 2 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu TRIB1

Target: TRIB1 (Tribbles Homolog 1 (TRIB1))

Andere Bezeichnung: TRIB1 (TRIB1 Produkte)

Synonyme: TRIB1 antikoerper, c8fw antikoerper, gig2 antikoerper, skip1 antikoerper, trb1 antikoerper, tribbles antikoerper, C8FW antikoerper, GIG2 antikoerper, SKIP1 antikoerper, TRB1 antikoerper, A530090O15Rik antikoerper, TRB-1 antikoerper, Trb1 antikoerper, Gig2 antikoerper, tribbles pseudokinase 1 antikoerper, tribbles pseudokinase 1 L homeolog antikoerper, tribbles homolog 1 (Drosophila) antikoerper, TRIB1 antikoerper, trib1 antikoerper, trib1.L antikoerper, Trib1 antikoerper

Hintergrund: TRIB1 antibody, also called gprotein coupled receptor induced, skip1, gig2, c8fwATP, functions in binding protein binding, protein kinase inhibitor activity, and protein serine/threonine kinase activities. Overexpression of TRIB1 in HeLa cells repressed the basal activity of the IL8 promoter by inhibiting AP1 activity. Overexpression of TRIB1 inhibited oncogenic Ras -driven AP1 activation and MEKK1-mediated AP1 activation. ERK activation was enhanced by TRIB1. Coimmunoprecipitation and yeast 2-hybrid assays showed that MEK1 interacted with both TRIB1 and TRIB3, and MKK4 interacted specifically with TRIB1. Cotransfection of MKK4 enhanced the level of TRIB1, indicating that the TRIB-MAPKK interaction stabilized TRIB1.

Molekulargewicht: 41 kDa

Gen-ID: 10221

UniProt: Q96RU8

Pathways: Smooth Muscle Cell Migration