This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This NR1I2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 100-127 amino acids from the Central region of human NR1I2.
NR1I2
Reaktivität: Human
WB
Wirt: Kaninchen
Polyclonal
unconjugated
Applikationshinweise
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:50~100
For FACS starting dilution is: 1:10~50
For IF starting dilution is: 1:10~50
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Buffer
Supplied in PBS with 0.09 % (W/V) sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C
Informationen zur Lagerung
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Target
NR1I2
(Nuclear Receptor Subfamily 1, Group I, Member 2 (NR1I2))
BXR antikoerper, ONR1 antikoerper, PAR antikoerper, PAR1 antikoerper, PAR2 antikoerper, PARq antikoerper, PRR antikoerper, PXR antikoerper, SAR antikoerper, SXR antikoerper, PXR.1 antikoerper, PXR.2 antikoerper, PXR1 antikoerper, mPXR antikoerper, bxr antikoerper, nr1i2 antikoerper, onr1 antikoerper, xonr1 antikoerper, nuclear receptor subfamily 1 group I member 2 antikoerper, nuclear receptor subfamily 1, group I, member 2 antikoerper, nuclear receptor subfamily 1 group I member 2 S homeolog antikoerper, NR1I2 antikoerper, Nr1i2 antikoerper, nr1i2.S antikoerper, nr1i2 antikoerper
Hintergrund
NR1I2 belongs to the nuclear receptor superfamily, members of which are transcription factors characterized by a ligand-binding domain and a DNA-binding domain. This protein is a transcriptional regulator of the cytochrome P450 gene CYP3A4, binding to the response element of the CYP3A4 promoter as a heterodimer with the 9-cis retinoic acid receptor RXR. It is activated by a range of compounds that induce CYP3A4, including dexamethasone and rifampicin.