Myosin IA Antikörper (AA 276-304)

Produktnummer ABIN5531626

Produktdetails anti-Myosin IA Antikörper

Target: Myosin IA (MYO1A)

Bindungsspezifität: AA 276-304

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Myosin IA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS)

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Immunogen: This MYO1A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 276-304 amino acids from the Central region of human MYO1A.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: For WB starting dilution is: 1:1000

For FACS starting dilution is: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 2 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu Myosin IA

Target: Myosin IA (MYO1A)

Andere Bezeichnung: MYO1A (MYO1A Produkte)

Synonyme: CG7438 antikoerper, Dm IA antikoerper, DmIA antikoerper, Dmel\\CG7438 antikoerper, DroMIA antikoerper, IA antikoerper, MYOIA antikoerper, Myo-IA antikoerper, Myo1A antikoerper, MyoIA antikoerper, MyoID antikoerper, myoID antikoerper, souther antikoerper, bbmi antikoerper, mihc antikoerper, myhl antikoerper, dfna48 antikoerper, MGC83822 antikoerper, MYO1A antikoerper, MGC79641 antikoerper, BBMI antikoerper, DFNA48 antikoerper, MIHC antikoerper, MYHL antikoerper, BBM-I antikoerper, Myhl antikoerper, Myh1 antikoerper, Myosin 31DF antikoerper, myosin IA L homeolog antikoerper, myosin IA antikoerper, Myo31DF antikoerper, myo1a.L antikoerper, MYO1A antikoerper, myo1a antikoerper, Myo1a antikoerper

Hintergrund: MYO1A belongs to the myosin superfamily. Myosins are molecular motors that, upon interaction with actin filaments, utilize energy from ATP hydrolysis to generate mechanical force. Each myosin has a conserved N-terminal motor domain that contains both ATP-binding and actin-binding sequences. Following the motor domain is a light-chain-binding 'neck' region containing 1-6 copies of a repeat element, the IQ motif, that serves as a binding site for calmodulin or other members of the EF-hand superfamily of calcium-binding proteins. At the C-terminus, each myosin class has a distinct tail domain that serves in dimerization, membrane binding, protein binding, and/or enzymatic activities and targets each myosin to its particular subcellular location. The kidney epithelial cell line, LLC-PK1-CL4 (CL4), forms a well ordered brush border (BB) on its apical surface. Experiments indicate that the brush border population of the protein turns over rapidly, while its head and tail domains interact transiently with the core actin and plasma membrane, respectively. A rapidly exchanging pool of the protein envelops an actin core bundle that, by comparison, is static in structure.

Molekulargewicht: 118 kDa

Gen-ID: 4640

UniProt: Q9UBC5

Pathways: Sensory Perception of Sound