This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This DMRT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 296-322 amino acids from the C-terminal region of human DMRT1.
DMRT1
Reaktivität: Human
ELISA
Wirt: Kaninchen
Polyclonal
HRP
Applikationshinweise
For WB starting dilution is: 1:1000
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
0.5 mg/mL
Buffer
Supplied in PBS with 0.09 % (W/V) sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C
Informationen zur Lagerung
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Target
DMRT1
(Doublesex and Mab-3 Related Transcription Factor 1 (DMRT1))
DMT1 antikoerper, DMRT1 antikoerper, zgc:136676 antikoerper, dmrt1 antikoerper, dmrt1-alpha antikoerper, dmt1 antikoerper, dmrt1-beta antikoerper, xdmrt1 antikoerper, doublesex and mab-3 related transcription factor 1 antikoerper, doublesex and mab-3 related transcription factor 1 L homeolog antikoerper, doublesex and mab-3 related transcription factor 1 S homeolog antikoerper, DMRT1 antikoerper, Dmrt1 antikoerper, dmrt1 antikoerper, dmrt1.L antikoerper, dmrt1.S antikoerper
Hintergrund
This gene is found in a cluster with two other members of the gene family, having in common a zinc finger-like DNA-binding motif (DM domain). The DM domain is an ancient, conserved component of the vertebrate sex-determining pathway that is also a key regulator of male development in flies and nematodes. This gene exhibits a gonad-specific and sexually dimorphic expression pattern. Defective testicular development and XY feminization occur when this gene is hemizygous.