Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Aufreinigung
This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This COL9A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 428-456 amino acids from the Central region of human COL9A1.
COL9A1
Reaktivität: Human
WB
Wirt: Maus
Polyclonal
unconjugated
Applikationshinweise
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
0.5 mg/mL
Buffer
Supplied in PBS with 0.09 % (W/V) sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C
Informationen zur Lagerung
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
cb339 antikoerper, sb:cb339 antikoerper, zgc:85892 antikoerper, wu:fa12a12 antikoerper, wu:fa12d02 antikoerper, wu:fc22c08 antikoerper, wu:fc38d08 antikoerper, edm6 antikoerper, MGC82441 antikoerper, DJ149L1.1.2 antikoerper, EDM6 antikoerper, MED antikoerper, STL4 antikoerper, Col9a-1 antikoerper, collagen, type IX, alpha 1b antikoerper, collagen, type IX, alpha 1 L homeolog antikoerper, collagen type IX alpha 1 chain antikoerper, collagen, type IX, alpha 1 antikoerper, collagen alpha-1(IX) chain antikoerper, col9a1b antikoerper, col9a1.L antikoerper, COL9A1 antikoerper, Col9a1 antikoerper, LOC101102992 antikoerper
Hintergrund
COL9A1 is one of the three alpha chains of type IX collagen, which is a minor (5-20 % ) collagen component of hyaline cartilage. Type IX collagen is usually found in tissues containing type II collagen, a fibrillar collagen. Studies in knockout mice have shown that synthesis of the alpha 1 chain is essential for assembly of type IX collagen molecules, a heterotrimeric molecule,and that lack of type IX collagen is associated with early onset osteoarthritis. Mutations in the COL9A1 gene are associated with osteoarthritis in humans, with multiple epiphyseal dysplasia, 6, a form of chondrodysplasia, and with Stickler syndrome, a disease characterized by ophthalmic, orofacial, articular, and auditory defects.