Neurocan Antikörper

Produktnummer ABIN5519042

Produktdetails anti-Neurocan Antikörper

Target: Neurocan (NCAN)

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Neurocan Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Verwendungszweck: Rabbit IgG polyclonal antibody for Neurocan detection. Tested with WB, IHC-P in Human,Mouse,Rat.

Sequenz: HENTWIGLND RIVERDFQWT DNTGLQFENW RENQPDNFFA

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Rabbit IgG polyclonal antibody for Neurocan detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: neurocan
Protein Name: Neurocan core protein

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence of human Neurocan (HENTWIGLNDRIVERDFQWTDNTGLQFENWRENQPDNFFA).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (SV0002-1) for IHC(P).

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Referenzen für anti-Neurocan Antikörper (ABIN5519042)

Wang, Zhang, Zhang, Fan, Shen, Hu, Chen: "Oxygen-glucose deprivation induced glial scar-like change in astrocytes." in: PLoS ONE, Vol. 7, Issue 5, pp. e37574, (2012) (PubMed).

Details zu Neurocan

Target: Neurocan (NCAN)

Andere Bezeichnung: NCAN (NCAN Produkte)

Synonyme: cspg3 antikoerper, ncan antikoerper, si:ch211-123b7.1 antikoerper, NCAN antikoerper, CSPG3 antikoerper, Cspg3 antikoerper, C230035B04 antikoerper, Cspg3-rs antikoerper, Tgfbit antikoerper, neurocan b antikoerper, neurocan antikoerper, ncanb antikoerper, NCAN antikoerper, Ncan antikoerper

Hintergrund: Neurocan core protein is a protein that in humans is encoded by the NCAN gene. Neurocan is a member of the lectican / chondroitin sulfate proteoglycan protein families and consists of neurocan core protein and chondroitin sulfate. It is thought to be involved in the modulation of cell adhesion and migration. In the human subjects, it was found that NCAN genotype was strongly associated with manic symptoms but not with depressive symptoms. In the mice, the absence of functional Neurocan resulted in a variety of manic-like behaviors, which could be normalized by administering lithium.

Synonyms: Neurocan core protein, Chondroitin sulfate proteoglycan 3, NCAN, CSPG3, NEUR

Gen-ID: 1463

UniProt: O14594

Pathways: Glycosaminoglycan Metabolic Process