CPI-17 Antikörper (AA 30-126)

Produktnummer ABIN5518865

Produktdetails anti-CPI-17 Antikörper

Target: CPI-17 (PPP1R14A) (Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 14A (PPP1R14A))

Bindungsspezifität: AA 30-126

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CPI-17 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Verwendungszweck: Rabbit IgG polyclonal antibody for Protein phosphatase 1 regulatory subunit 14A(PPP1R14A) detection. Tested with WB, IHC-P in Human,Mouse,Rat.

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Rabbit IgG polyclonal antibody for Protein phosphatase 1 regulatory subunit 14A(PPP1R14A) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: protein phosphatase 1 regulatory inhibitor subunit 14A
Protein Name: Protein phosphatase 1 regulatory subunit 14A

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human CPI17 alpha recombinant protein (Position: L30-Q126). Human CPI17 alpha shares 83.5% and 84.5% amino acid (aa) sequence identity with mouse and rat CPI17 alpha, respectively.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Details zu CPI-17

Target: CPI-17 (PPP1R14A) (Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 14A (PPP1R14A))

Andere Bezeichnung: PPP1R14A (PPP1R14A Produkte)

Synonyme: MGC81874 antikoerper, cpi-17 antikoerper, ppp1inl antikoerper, CPI-17 antikoerper, im:7147597 antikoerper, ppp1r14a antikoerper, zgc:110700 antikoerper, PPP1R14A antikoerper, CPI17 antikoerper, PPP1INL antikoerper, Cpi17 antikoerper, 1110001M11Rik antikoerper, protein phosphatase 1 regulatory inhibitor subunit 14A L homeolog antikoerper, protein phosphatase 1 regulatory inhibitor subunit 14A antikoerper, protein phosphatase 1, regulatory (inhibitor) subunit 14Aa antikoerper, protein phosphatase 1, regulatory (inhibitor) subunit 14A antikoerper, ppp1r14a.L antikoerper, ppp1r14a antikoerper, ppp1r14aa antikoerper, PPP1R14A antikoerper, Ppp1r14a antikoerper

Hintergrund: Protein phosphatase 1 regulatory subunit 14A, also known as CPI-17, is a protein that in humans is encoded by the PPP1R14A gene. This protein is an inhibitor of smooth muscle myosin phosphatase, and has higher inhibitory activity when phosphorylated. Inhibition of myosin phosphatase leads to increased myosin phosphorylation and enhanced smooth muscle contraction. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

Synonyms: 17-KDa protein | CPI 17 alpha | CPI 17 | CPI 17alpha | CPI-17 | CPI17 | PPP1INL | Ppp1r14a | Q96A00

Gen-ID: 94274

UniProt: Q96A00