BAG1 Antikörper (C-Term)

Produktnummer ABIN5518811

Produktdetails anti-BAG1 Antikörper

Target: BAG1 (BCL2-Associated Athanogene (BAG1))

Bindungsspezifität: AA 323-345, C-Term

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BAG1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Verwendungszweck: Rabbit IgG polyclonal antibody for BAG family molecular chaperone regulator 1(BAG1) detection. Tested with WB, IHC-P in Human,Mouse,Rat.

Sequenz: DTVEQNICQE TERLQSTNFA LAE

Kreuzreaktivität (Details): Predicted Cross Reactivity: human
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.

Produktmerkmale: Rabbit IgG polyclonal antibody for BAG family molecular chaperone regulator 1(BAG1) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: BCL2 associated athanogene 1
Protein Name: BAG family molecular chaperone regulator 1

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human Bag1 (323-345aa DTVEQNICQETERLQSTNFALAE), different from the related mouse sequence by two amino acids, and from the related rat sequence by three amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Rat, Predicted Species: Human
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Mouse, Rat, Predicted Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Referenzen für anti-BAG1 Antikörper (ABIN5518811)

Bai, Yi, Li, Sui: "Clinicopathologic significance of BAG1 and TIMP3 expression in colon carcinoma." in: World journal of gastroenterology, Vol. 13, Issue 28, pp. 3883-5, (2007) (PubMed).

Details zu BAG1

Target: BAG1 (BCL2-Associated Athanogene (BAG1))

Andere Bezeichnung: BAG1 (BAG1 Produkte)

Synonyme: BAG-1 antikoerper, HAP antikoerper, RAP46 antikoerper, Rap46 antikoerper, Bag-1 antikoerper, ATBAG1 antikoerper, BCL-2-associated athanogene 1 antikoerper, MSG15.15 antikoerper, MSG15_15 antikoerper, im:7148830 antikoerper, si:dkey-216e9.4 antikoerper, BCL2 associated athanogene 1 antikoerper, putative bcl2-associated athanogene antikoerper, BCL2-associated athanogene 1 antikoerper, Bcl2 associated athanogene 1 antikoerper, BAG family molecular chaperone regulator 1 antikoerper, BCL-2-associated athanogene 1 antikoerper, BAG1 antikoerper, Smp_005900 antikoerper, Bag1 antikoerper, bag-1 antikoerper, LOC781741 antikoerper, bag1 antikoerper

Hintergrund: BAG family molecular chaperone regulator 1 (BAG1) is a protein that in humans is encoded by the BAG1 gene. Human BAG1 is mapped to chromosome 9p12, a region associated with hereditary disorders that may involve developmental dysregulation of programmed cell death. The Bag1 protein is rich in glutamic acid residues. Its deduced 274-amino acid protein has a calculated molecular mass of 31 KD. Being the BCL-2-associated athanogene, Bag1 enhances the anti-apoptotic effects of BCL2 and represents a link between growth factor receptors and anti-apoptotic mechanisms.

Synonyms: BAG family molecular chaperone regulator 1 | BAG-1 | Bcl-2-associated athanogene 1 | BAG1 | HAP | Q99933

Gen-ID: 573

UniProt: Q99933