PES1 Antikörper (Middle Region)

Produktnummer ABIN5517691

Produktdetails anti-PES1 Antikörper

Target: PES1 (Pescadillo Ribosomal Biogenesis Factor 1 (PES1))

Bindungsspezifität: Middle Region

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PES1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: LLALQRGEDP GNLNESEEEE EEDDNNEGDG DEEGENEEEE EDAEAGSEKE

Aufreinigung: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human PES1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu PES1

Target: PES1 (Pescadillo Ribosomal Biogenesis Factor 1 (PES1))

Andere Bezeichnung: PES1 (PES1 Produkte)

Synonyme: PES antikoerper, pes antikoerper, pes1 antikoerper, pescadillo ribosomal biogenesis factor 1 antikoerper, pescadillo ribosomal biogenesis factor 1 S homeolog antikoerper, Pescadillo antikoerper, PES1 antikoerper, Pes1 antikoerper, pes1.S antikoerper, pesc antikoerper

Hintergrund: This gene encodes a nuclear protein that contains a breast cancer associated gene 1 (BRCA1) C-terminal interaction domain. The encoded protein interacts with BOP1 and WDR12 to form the PeBoW complex, which plays a critical role in cell proliferation via pre-rRNA processing and 60S ribosomal subunit maturation. Expression of this gene may play an important role in breast cancer proliferation and tumorigenicity. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Pseudogenes of this gene are located on the long arm of chromosome 4 and the short arm of chromosome 9.

Alias Symbols: PES

Protein Size: 167

Gen-ID: 23481

NCBI Accession: NM_001243225, NP_001230154

UniProt: O00541