PLOD2 Antikörper (C-Term)

Produktnummer ABIN5517437

Produktdetails anti-PLOD2 Antikörper

Target: PLOD2 (Procollagen-Lysine 2-Oxoglutarate 5-Dioxygenase 2 (PLOD2))

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PLOD2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: PIFSEKACDE LVEEMEHYGK WSGGKHHDSR ISGGYENVPT DDIHMKQVDL

Produktmerkmale: This is a rabbit polyclonal antibody against PLOD2. It was validated on Western Blot.

Aufreinigung: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human PLOD2

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu PLOD2

Target: PLOD2 (Procollagen-Lysine 2-Oxoglutarate 5-Dioxygenase 2 (PLOD2))

Andere Bezeichnung: PLOD2 (PLOD2 Produkte)

Synonyme: D530025C14Rik antikoerper, LH2 antikoerper, Plod-2 antikoerper, TLH antikoerper, procollagen lysine, 2-oxoglutarate 5-dioxygenase 2 antikoerper, procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 antikoerper, Plod2 antikoerper, PLOD2 antikoerper

Hintergrund: The protein encoded by this gene is a membrane-bound homodimeric enzyme that is localized to the cisternae of the rough endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers-Danlos syndrome type VIB have deficiencies in lysyl hydroxylase activity. Mutations in the coding region of this gene are associated with Bruck syndrome. Alternative splicing results in multiple transcript variants encoding different isoforms.

Alias Symbols: PLOD2,

Protein Interaction Partner: ITGB1BP2, SUPT5H, CSDE1, SF1, UGP2, TPP2, VASN, RNF123, NUSAP1, SAMHD1, DNPEP, GANAB, SWAP70, XPO7, PACSIN2, FAF1, HSPH1, SEC23A, PRMT3, FARSB, USP15, RANBP3, SET, RPL24, PTPN12, NCL, NARS, JUP, GART, XRCC6, AP2B1, gag-pol, UBL4A, OS9, FBXO6, UBC, VHL, Fa

Protein Size: 737

Gen-ID: 5352

UniProt: O00469

Pathways: SARS-CoV-2 Protein Interaktom