RASGRP2 Antikörper (Middle Region)

Produktnummer ABIN5517288

Produktdetails anti-RASGRP2 Antikörper

Target: RASGRP2 (RAS Guanyl Releasing Protein 2 (Calcium and DAG-Regulated) (RASGRP2))

Bindungsspezifität: Middle Region

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RASGRP2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: RPPVQANPDL LSLLTVSLDQ YQTEDELYQL SLQREPRSKS SPTSPTSCTP

Aufreinigung: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human RASGRP2

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu RASGRP2

Target: RASGRP2 (RAS Guanyl Releasing Protein 2 (Calcium and DAG-Regulated) (RASGRP2))

Andere Bezeichnung: RASGRP2 (RASGRP2 Produkte)

Synonyme: CALDAG-GEFI antikoerper, CDC25L antikoerper, xrasgrp2 antikoerper, RASGRP2 antikoerper, Caldaggef1 antikoerper, CalDAG-GEFI antikoerper, rasgrp2 antikoerper, RAS guanyl releasing protein 2 antikoerper, RAS guanyl releasing protein 2 (calcium and DAG-regulated) S homeolog antikoerper, RAS, guanyl releasing protein 2 antikoerper, RAS guanyl releasing protein 2 (calcium and DAG-regulated) L homeolog antikoerper, RASGRP2 antikoerper, rasgrp2.S antikoerper, Rasgrp2 antikoerper, rasgrp2.L antikoerper

Hintergrund: The protein encoded by this gene is a brain-enriched nucleotide exchanged factor that contains an N-terminal GEF domain, 2 tandem repeats of EF-hand calcium-binding motifs, and a C-terminal diacylglycerol/phorbol ester-binding domain. This protein can activate small GTPases, including RAS and RAP1/RAS3. The nucleotide exchange activity of this protein can be stimulated by calcium and diacylglycerol. Four alternatively spliced transcript variants encoding two different isoforms have been found for this gene.

Alias Symbols: CDC25L, CALDAG-GEFI

Protein Size: 609

Gen-ID: 10235

NCBI Accession: NM_001098670, NP_001092140

UniProt: Q7LDG7

Pathways: T-Zell Rezeptor Signalweg