SIP1 Antikörper (Middle Region)
-
- Target Alle SIP1 (GEMIN2) Antikörper anzeigen
- SIP1 (GEMIN2) (Gem (Nuclear Organelle) Associated Protein 2 (GEMIN2))
-
Bindungsspezifität
- Middle Region
-
Reaktivität
- Human
-
Wirt
- Kaninchen
-
Klonalität
- Polyklonal
-
Konjugat
- Dieser SIP1 Antikörper ist unkonjugiert
-
Applikation
- Western Blotting (WB)
- Sequenz
- QQQQVAQFST VRQNVNKHRS HWKSQQLDSN VTMPKSEDEE GWKKFCLGEK
- Aufreinigung
- Affinity purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human SIP1
- Top Product
- Discover our top product GEMIN2 Primärantikörper
-
-
- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
- Target
- SIP1 (GEMIN2) (Gem (Nuclear Organelle) Associated Protein 2 (GEMIN2))
- Andere Bezeichnung
- SIP1 (GEMIN2 Produkte)
- Synonyme
- SIP1 antikoerper, SIP1-delta antikoerper, 1700012N19Rik antikoerper, Sip1 antikoerper, sip1 antikoerper, sip1-delta antikoerper, wu:fc52a05 antikoerper, zgc:110274 antikoerper, gem nuclear organelle associated protein 2 antikoerper, gem (nuclear organelle) associated protein 2 antikoerper, gem nuclear organelle associated protein 2 S homeolog antikoerper, GEMIN2 antikoerper, Gemin2 antikoerper, gemin2.S antikoerper, gemin2 antikoerper
- Hintergrund
-
This gene encodes one of the proteins found in the SMN complex, which consists of several gemin proteins and the protein known as the survival of motor neuron protein. The SMN complex is localized to a subnuclear compartment called gems (gemini of coiled bodies) and is required for assembly of spliceosomal snRNPs and for pre-mRNA splicing. This protein interacts directly with the survival of motor neuron protein and it is required for formation of the SMN complex. A knockout mouse targeting the mouse homolog of this gene exhibited disrupted snRNP assembly and motor neuron degeneration.
Alias Symbols: SIP1, SIP1-delta
Protein Size: 280 - Gen-ID
- 8487
- NCBI Accession
- NM_001009182, NP_001009182
- UniProt
- O14893
- Pathways
- Ribonucleoprotein Complex Subunit Organization, Tube Formation
-