EYA4 Antikörper (Middle Region)

Produktnummer ABIN5516717

Produktdetails anti-EYA4 Antikörper

Target: EYA4 (Eyes Absent Homolog 4 (EYA4))

Bindungsspezifität: Middle Region

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EYA4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: DERTCRSSGS KSRGRGRKNN PSPPPDSDLE RVFVWDLDET IIVFHSLLTG

Aufreinigung: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human EYA4

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu EYA4

Target: EYA4 (Eyes Absent Homolog 4 (EYA4))

Andere Bezeichnung: EYA4 (EYA4 Produkte)

Synonyme: B130023L16Rik antikoerper, CMD1J antikoerper, DFNA10 antikoerper, EYA transcriptional coactivator and phosphatase 4 antikoerper, Eya4 antikoerper, EYA4 antikoerper

Hintergrund: This gene encodes a member of the eyes absent (EYA) family of proteins. The encoded protein may act as a transcriptional activator through its protein phosphatase activity, and it may be important for eye development, and for continued function of the mature organ of Corti. Mutations in this gene are associated with postlingual, progressive, autosomal dominant hearing loss at the deafness, autosomal dominant non-syndromic sensorineural 10 locus. The encoded protein is also a putative oncogene that mediates DNA repair, apoptosis, and innate immunity following DNA damage, cellular damage, and viral attack. Defects in this gene are also associated with dilated cardiomyopathy 1J. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Alias Symbols: CMD1J, DFNA10,

Protein Size: 616

Gen-ID: 2070

NCBI Accession: NM_001301012, NP_001287941

Pathways: Sensory Perception of Sound