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DUX4 Antikörper (Middle Region)
DUX4
Reaktivität: Human
WB
Wirt: Kaninchen
Polyclonal
unconjugated
Produktnummer ABIN5516703
Produktdetails anti-DUX4 Antikörper
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Target
Alle DUX4 Antikörper anzeigen
DUX4
(Double Homeobox 4 (DUX4))
Bindungsspezifität
Alle Epitope für DUX4 Antikörper
Middle Region
Reaktivität
Alle Reaktivitäten für DUX4 Antikörper
Human
Wirt
Alle Wirte für DUX4 Antikörper
Kaninchen
Klonalität
Alle Klonalitäten für DUX4 Antikörper
Polyklonal
Konjugat
Alle Konjugate für DUX4 Antikörper
Dieser DUX4 Antikörper ist unkonjugiert
Applikation
Alle Applikationen für DUX4 Antikörper
Western Blotting (WB)
Sequenz
ESRPWPGRRG PPEGRRKRTA VTGSQTALLL RAFEKDRFPG IAAREELARE
Homologie
Human: 85%
Produktmerkmale
This is a rabbit polyclonal antibody against DUX4. It was validated on Western Blot.
Aufreinigung
Affinity Purified
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human DUX4
Top Product
Discover our top product DUX4 Primärantikörper
Alternativen
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Anwendungsinformationen
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Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Format
Liquid
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Details zu DUX4
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Target
DUX4
(Double Homeobox 4 (DUX4))
Andere Bezeichnung
DUX4 (DUX4 Produkte )
Synonyme
DUX4 antikoerper, DUX4L antikoerper, double homeobox, 4 antikoerper, double homeobox 4 antikoerper, DUX4 antikoerper
Hintergrund
This gene is located within a D4Z4 repeat array in the subtelomeric region of chromosome 4q. The D4Z4 repeat is polymorphic in length, a similar D4Z4 repeat array has been identified on chromosome 10. Each D4Z4 repeat unit has an open reading frame (named DUX4) that encodes two homeoboxes, the repeat-array and ORF is conserved in other mammals. The encoded protein has been reported to function as a transcriptional activator of paired-like homeodomain transcription factor 1 (PITX1, GeneID 5307). Contraction of the macrosatellite repeat causes autosomal dominant facioscapulohumeral muscular dystrophy (FSHD). Alternative splicing results in multiple transcript variants. Alias Symbols: DUX4L Protein Size: 424
Gen-ID
100288687
NCBI Accession
NM_001293798 , NP_001280727
UniProt
Q9UBX2
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