RASA4 Antikörper (Middle Region)

Produktnummer ABIN5516667

Produktdetails anti-RASA4 Antikörper

Target: RASA4 (RAS P21 Protein Activator 4 (RASA4))

Bindungsspezifität: Middle Region

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RASA4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: EEGWFRLQPD QSKSRRHDEG NLGSLQLEVR LRDETVLPSS YYQPLVHLLC

Aufreinigung: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human RASA4

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 16 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu RASA4

Target: RASA4 (RAS P21 Protein Activator 4 (RASA4))

Andere Bezeichnung: RASA4 (RASA4 Produkte)

Synonyme: CAPRI antikoerper, GAPL antikoerper, AA793972 antikoerper, AW112107 antikoerper, BB079060 antikoerper, mKIAA0538 antikoerper, RAS p21 protein activator 4 antikoerper, RASA4 antikoerper, Rasa4 antikoerper

Hintergrund: This gene encodes a member of the GAP1 family of GTPase-activating proteins that suppresses the Ras/mitogen-activated protein kinase pathway in response to Ca(2+). Stimuli that increase intracellular Ca(2+) levels result in the translocation of this protein to the plasma membrane, where it activates Ras GTPase activity. Consequently, Ras is converted from the active GTP-bound state to the inactive GDP-bound state and no longer activates downstream pathways that regulate gene expression, cell growth, and differentiation. Multiple transcript variants encoding different isoforms have been found for this gene.

Alias Symbols: GAPL, CAPRI,

Protein Size: 803

Gen-ID: 10156

NCBI Accession: NM_001079877, NP_001073346

UniProt: O43374