FBXO22 Antikörper (Middle Region)

Produktnummer ABIN5516515

Produktdetails anti-FBXO22 Antikörper

Target: FBXO22 (F-Box Protein 22 (FBXO22))

Bindungsspezifität: Middle Region

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FBXO22 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: VVTPMGSGSN RPQEIEIGES GFALLFPQIE GIKIQPFHFI KDPKNLTLER

Produktmerkmale: This is a rabbit polyclonal antibody against FBX22. It was validated on Western Blot.

Aufreinigung: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human FBX22

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu FBXO22

Target: FBXO22 (F-Box Protein 22 (FBXO22))

Andere Bezeichnung: FBX22 (FBXO22 Produkte)

Synonyme: FBXO22 antikoerper, DKFZp469L0535 antikoerper, fbxo22 antikoerper, MGC146708 antikoerper, si:busm1-132m23.3 antikoerper, FBX22 antikoerper, FISTC1 antikoerper, 0610033L19Rik antikoerper, 1600016C16Rik antikoerper, F-box protein 22 antikoerper, FBXO22 antikoerper, fbxo22 antikoerper, Fbxo22 antikoerper

Hintergrund: This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and, as a transcriptional target of the tumor protein p53, is thought to be involved in degradation of specific proteins in response to p53 induction. Alternative splicing results in multiple transcript variants.

Alias Symbols: FBXO22, FBX22,

Protein Interaction Partner: Srr, UBC, CUL1, SKP1, NEDD8, COPS5, COPS6, RBX1,

Protein Size: 403

Gen-ID: 26263

NCBI Accession: NP_671717

UniProt: Q8NEZ5

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development