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CDK2AP1 Antikörper (Middle Region)
CDK2AP1
Reaktivität: Human
WB
Wirt: Kaninchen
Polyclonal
unconjugated
Produktnummer ABIN5516286
Produktdetails anti-CDK2AP1 Antikörper
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Target
Alle CDK2AP1 Antikörper anzeigen
CDK2AP1
(Cyclin-Dependent Kinase 2 Associated Protein 1 (CDK2AP1))
Bindungsspezifität
Alle Epitope für CDK2AP1 Antikörper
Middle Region
Reaktivität
Alle Reaktivitäten für CDK2AP1 Antikörper
Human
Wirt
Alle Wirte für CDK2AP1 Antikörper
Kaninchen
Klonalität
Alle Klonalitäten für CDK2AP1 Antikörper
Polyklonal
Konjugat
Alle Konjugate für CDK2AP1 Antikörper
Dieser CDK2AP1 Antikörper ist unkonjugiert
Applikation
Alle Applikationen für CDK2AP1 Antikörper
Western Blotting (WB)
Sequenz
SPSTSMATSS QYRQLLSDYG PPSLGYTQGT GNSQVPQSKY AELLAIIEEL
Aufreinigung
Affinity purified
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human CDK2AP1
Top Product
Discover our top product CDK2AP1 Primärantikörper
Alternativen
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Anwendungsinformationen
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Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Format
Liquid
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Details zu CDK2AP1
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Target
CDK2AP1
(Cyclin-Dependent Kinase 2 Associated Protein 1 (CDK2AP1))
Andere Bezeichnung
CDK2AP1 (CDK2AP1 Produkte )
Synonyme
MGC64532 antikoerper, doc1 antikoerper, st19 antikoerper, doc-1 antikoerper, dorc1 antikoerper, p12doc-1 antikoerper, Apc10 antikoerper, Cdkap1 antikoerper, DORC1 antikoerper, Doc1 antikoerper, ST19 antikoerper, p12 antikoerper, DOC1 antikoerper, p12DOC-1 antikoerper, cyclin-dependent kinase 2 associated protein 1 S homeolog antikoerper, cyclin dependent kinase 2 associated protein 1 antikoerper, cyclin dependent kinase 2 associated protein 1 pseudogene antikoerper, cyclin-dependent kinase 2 associated protein 1 antikoerper, CDK2 (cyclin-dependent kinase 2)-associated protein 1 antikoerper, cdk2ap1.S antikoerper, CDK2AP1 antikoerper, LOC475806 antikoerper, cdk2ap1 antikoerper, Cdk2ap1 antikoerper
Hintergrund
The protein encoded by this gene is a cyclin-dependent kinase 2 (CDK2) -associated protein which is thought to negatively regulate CDK2 activity by sequestering monomeric CDK2, and targeting CDK2 for proteolysis. This protein was found to also interact with DNA polymerase alpha/primase and mediate the phosphorylation of the large p180 subunit, which suggests a regulatory role in DNA replication during the S-phase of the cell cycle. This protein also forms a core subunit of the nucleosome remodeling and histone deacetylation (NURD) complex that epigenetically regulates embryonic stem cell differentiation. This gene thus plays a role in both cell-cycle and epigenetic regulation. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Alias Symbols: DOC1, ST19, DORC1, doc-1, p12DOC-1 Protein Size: 115
Gen-ID
8099
NCBI Accession
NM_001270433 , NP_001257362
UniProt
O14519
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