CDK2AP1 Antikörper (Middle Region)

Produktnummer ABIN5516286

Produktdetails anti-CDK2AP1 Antikörper

Target: CDK2AP1 (Cyclin-Dependent Kinase 2 Associated Protein 1 (CDK2AP1))

Bindungsspezifität: Middle Region

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CDK2AP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: SPSTSMATSS QYRQLLSDYG PPSLGYTQGT GNSQVPQSKY AELLAIIEEL

Aufreinigung: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human CDK2AP1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu CDK2AP1

Target: CDK2AP1 (Cyclin-Dependent Kinase 2 Associated Protein 1 (CDK2AP1))

Andere Bezeichnung: CDK2AP1 (CDK2AP1 Produkte)

Synonyme: MGC64532 antikoerper, doc1 antikoerper, st19 antikoerper, doc-1 antikoerper, dorc1 antikoerper, p12doc-1 antikoerper, Apc10 antikoerper, Cdkap1 antikoerper, DORC1 antikoerper, Doc1 antikoerper, ST19 antikoerper, p12 antikoerper, DOC1 antikoerper, p12DOC-1 antikoerper, cyclin-dependent kinase 2 associated protein 1 S homeolog antikoerper, cyclin dependent kinase 2 associated protein 1 antikoerper, cyclin dependent kinase 2 associated protein 1 pseudogene antikoerper, cyclin-dependent kinase 2 associated protein 1 antikoerper, CDK2 (cyclin-dependent kinase 2)-associated protein 1 antikoerper, cdk2ap1.S antikoerper, CDK2AP1 antikoerper, LOC475806 antikoerper, cdk2ap1 antikoerper, Cdk2ap1 antikoerper

Hintergrund: The protein encoded by this gene is a cyclin-dependent kinase 2 (CDK2) -associated protein which is thought to negatively regulate CDK2 activity by sequestering monomeric CDK2, and targeting CDK2 for proteolysis. This protein was found to also interact with DNA polymerase alpha/primase and mediate the phosphorylation of the large p180 subunit, which suggests a regulatory role in DNA replication during the S-phase of the cell cycle. This protein also forms a core subunit of the nucleosome remodeling and histone deacetylation (NURD) complex that epigenetically regulates embryonic stem cell differentiation. This gene thus plays a role in both cell-cycle and epigenetic regulation. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Alias Symbols: DOC1, ST19, DORC1, doc-1, p12DOC-1

Protein Size: 115

Gen-ID: 8099

NCBI Accession: NM_001270433, NP_001257362

UniProt: O14519