TNRC6B Antikörper (Middle Region)

Produktnummer ABIN5516264

Produktdetails anti-TNRC6B Antikörper

Target: TNRC6B (Trinucleotide Repeat Containing 6B (TNRC6B))

Bindungsspezifität: Middle Region

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TNRC6B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: STEWKDPKNT GGWNDYKNNN SSNWGGGRPD EKTPSSWNEN PSKDQGWGGG

Aufreinigung: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human TNRC6B

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu TNRC6B

Target: TNRC6B (Trinucleotide Repeat Containing 6B (TNRC6B))

Andere Bezeichnung: TNRC6B (TNRC6B Produkte)

Synonyme: hm:zeh0114 antikoerper, im:6968518 antikoerper, wu:fa01f05 antikoerper, 2700090M07Rik antikoerper, A730065C02Rik antikoerper, AI848765 antikoerper, D230019K20Rik antikoerper, Cbl27 antikoerper, trinucleotide repeat containing 6b antikoerper, trinucleotide repeat containing 6B antikoerper, trinucleotide repeat containing 6B S homeolog antikoerper, tnrc6b antikoerper, TNRC6B antikoerper, tnrc6b.S antikoerper, Tnrc6b antikoerper

Hintergrund: Plays a role in RNA-mediated gene silencing by both micro-RNAs (miRNAs) and short interfering RNAs (siRNAs). Required for miRNA-dependent translational repression and siRNA-dependent endonucleolytic cleavage of complementary mRNAs by argonaute family proteins. As scaffoldng protein associates with argonaute proteins bound to partially complementary mRNAs and simultaneously can recruit CCR4-NOT and PAN deadenylase complexes.

Protein Size: 1029

Gen-ID: 23112

NCBI Accession: NM_001024843, NP_001020014

Pathways: Fc-epsilon Rezeptor Signalübertragung, Regulatorische RNA Pathways, EGFR Signaling Pathway