WAPAL Antikörper (Middle Region)

Produktnummer ABIN5516204

Produktdetails anti-WAPAL Antikörper

Target: WAPAL (Wings Apart-Like Protein Homolog (WAPAL))

Bindungsspezifität: Middle Region

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser WAPAL Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: KSKKDVKLEF FGFEDHETGG DEGGSGSSNY KIKYFGFDDL SESEDDEDDD

Produktmerkmale: This is a rabbit polyclonal antibody against WAPL. It was validated on Western Blot.

Aufreinigung: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human WAPL

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu WAPAL

Target: WAPAL (Wings Apart-Like Protein Homolog (WAPAL))

Andere Bezeichnung: WAPL (WAPAL Produkte)

Synonyme: RGD1308960 antikoerper, FOE antikoerper, KIAA0261 antikoerper, WAPL antikoerper, 2410073G16 antikoerper, A530089A20Rik antikoerper, BC037674 antikoerper, mKIAA0261 antikoerper, mWAPL antikoerper, WAPL cohesin release factor antikoerper, Wapl antikoerper, WAPL antikoerper, wapl antikoerper

Hintergrund: WAPL is a regulator of sister chromatid cohesion in mitosis which negatively regulates cohesin association with chromatin. It is involved in both sister chromatid cohesion during interphase and sister- chromatid resolution during early stages of mitosis. It couples DNA replication to sister chromatid cohesion. Cohesion ensures that chromosome partitioning is accurate in both meiotic and mitotic cells and plays an important role in DNA repair.

Alias Symbols: WAPAL, FOE, KIAA0261, WAPL,

Protein Interaction Partner: UBC, RPA3, RPA2, RPA1, XRN1, PDS5A, SMC3, VCP, VPS16, WRAP53, USP15, USP10, NSMCE2, ELAVL1, SUMO2, RAD21, ARAP1, Stag2, WAPAL, PDS5B, STAG1, SMC1A, SRRM1,

Protein Size: 1190

Gen-ID: 23063

NCBI Accession: NP_055860

UniProt: Q7Z5K2

Pathways: Chromatin Binding