VPS72 Antikörper (N-Term)

Produktnummer ABIN5516202

Produktdetails anti-VPS72 Antikörper

Target: VPS72 (Vacuolar Protein Sorting 72 Homolog (S. Cerevisiae) (VPS72))

Bindungsspezifität: N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser VPS72 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: GLLEAEEEDE FYQTTYGGFT EESGDDEYQG DQSDTEDEVD SDFDIDEGDE

Produktmerkmale: This is a rabbit polyclonal antibody against VPS72. It was validated on Western Blot.

Aufreinigung: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human VPS72

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu VPS72

Target: VPS72 (Vacuolar Protein Sorting 72 Homolog (S. Cerevisiae) (VPS72))

Andere Bezeichnung: VPS72 (VPS72 Produkte)

Synonyme: CG4621 antikoerper, Dmel\\CG4621 antikoerper, dYL-1 antikoerper, vps72 antikoerper, MGC82727 antikoerper, Vps72 antikoerper, YL-1 antikoerper, ACYPI009531 antikoerper, Tcfl1 antikoerper, CFL1 antikoerper, Swc2 antikoerper, TCFL1 antikoerper, YL1 antikoerper, si:dkeyp-24a7.1 antikoerper, CG4621 gene product from transcript CG4621-RB antikoerper, vacuolar protein sorting 72 homolog L homeolog antikoerper, potential vacuolar protein sorting protein antikoerper, vacuolar protein sorting 72 homolog antikoerper, vacuolar protein sorting-associated protein 72 homolog antikoerper, vacuolar protein sorting 72 antikoerper, vacuolar protein sorting 72 homolog S homeolog antikoerper, vacuolar protein sorting 72 homolog (S. cerevisiae) antikoerper, YL-1 antikoerper, vps72.L antikoerper, VPS72 antikoerper, Vps72 antikoerper, vps72.S antikoerper, vps72 antikoerper

Hintergrund: The protein encoded by this gene is a shared subunit of two multi-component complexes, the histone acetyltransferase complex TRRAP/TIP60 as well as the chromatin remodeling SRCAP-containing complex. The TRRAP/TIP60 complex acetylates nucleosomal histones important for transcriptional regulation, double strand DNA break repair and apoptosis. The SRCAP-containing complex catalyzes the exchange of histone H2A with the histone variant Htz1 (H2AFZ) into nucleosomes. This protein may be responsible for binding H2AFZ, which has a role in chromosome segregation. This protein may also have a role in regulating long-term hematopoietic stem cell activity. Alternative splicing results in multiple transcript variants that encode different protein isoforms.

Alias Symbols: TCFL1, YL1

Protein Size: 364

Gen-ID: 6944

NCBI Accession: NP_005988

UniProt: Q15906

Pathways: Stem Cell Maintenance