Translin Antikörper (Middle Region)

Produktnummer ABIN5515344

Produktdetails anti-Translin Antikörper

Target: Translin (TSN)

Bindungsspezifität: Middle Region

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Translin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: VNSVTAGDYS RPLHISTFIN ELDSGFRLLN LKNDSLRKRY DGLKYDVKKV

Aufreinigung: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human TSN

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu Translin

Target: Translin (TSN)

Andere Bezeichnung: TSN (TSN Produkte)

Synonyme: tsn antikoerper, MGC52533 antikoerper, TSN antikoerper, CG11761 antikoerper, Dmel\\CG11761 antikoerper, TB-RBP antikoerper, BCLF-1 antikoerper, C3PO antikoerper, RCHF1 antikoerper, REHF-1 antikoerper, TBRBP antikoerper, TRSLN antikoerper, 2610034C24Rik antikoerper, AU040286 antikoerper, translin L homeolog antikoerper, translin antikoerper, haloacid dehalogenase antikoerper, Translin antikoerper, tsn.L antikoerper, TSN antikoerper, trsn antikoerper, MMAH_RS03470 antikoerper, TAGG_RS05275 antikoerper, Igag_0962 antikoerper, MFER_RS03645 antikoerper, DESMU_RS01315 antikoerper, ARCVE_RS05265 antikoerper, MZHIL_RS01310 antikoerper, Tsn antikoerper

Hintergrund: This gene encodes a DNA-binding protein which specifically recognizes conserved target sequences at the breakpoint junction of chromosomal translocations. Translin polypeptides form a multimeric structure that is responsible for its DNA-binding activity. Recombination-associated motifs and translin-binding sites are present at recombination hotspots and may serve as indicators of breakpoints in genes which are fused by translocations. These binding activities may play a crucial role in chromosomal translocation in lymphoid neoplasms. This protein encoded by this gene, when complexed with translin-associated protein X, also forms a Mg ion-dependent endoribonuclease that promotes RNA-induced silencing complex (RISC) activation. Alternative splicing results in multiple transcript variants.

Alias Symbols: C3PO, RCHF1, TBRBP, TRSLN, BCLF-1, REHF-1

Protein Size: 228

Gen-ID: 7247

NCBI Accession: NM_001261401, NP_001248330

UniProt: Q15631