SAFB Antikörper (Middle Region)

Produktnummer ABIN5515130

Produktdetails anti-SAFB Antikörper

Target: SAFB (Scaffold Attachment Factor B (SAFB))

Bindungsspezifität: Middle Region

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SAFB Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: TELHGKMISV EKAKNEPVGK KTSDKRDSDG KKEKSSNSDR STNLKRDDKC

Produktmerkmale: This is a rabbit polyclonal antibody against SAFB1. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human SAFB1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu SAFB

Target: SAFB (Scaffold Attachment Factor B (SAFB))

Andere Bezeichnung: SAFB1 (SAFB Produkte)

Synonyme: HAP antikoerper, HET antikoerper, SAF-B1 antikoerper, SAFB1 antikoerper, 3110021E02Rik antikoerper, 5330423C17Rik antikoerper, AU018122 antikoerper, D18386 antikoerper, E130307D12 antikoerper, zgc:55387 antikoerper, wu:fb40a03 antikoerper, wu:fd42g06 antikoerper, SAFB2 antikoerper, SAFB antikoerper, scaffold attachment factor B antikoerper, scaffold attachment factor B S homeolog antikoerper, SAFB-like transcription modulator antikoerper, Scaffold attachment factor B antikoerper, SAFB antikoerper, Safb antikoerper, safb antikoerper, safb.S antikoerper, LOC5570070 antikoerper, CpipJ_CPIJ017179 antikoerper, Bm1_49330 antikoerper, LOAG_00080 antikoerper

Hintergrund: This gene encodes a DNA-binding protein which has high specificity for scaffold or matrix attachment region DNA elements (S/MAR DNA). This protein is thought to be involved in attaching the base of chromatin loops to the nuclear matrix but there is conflicting evidence as to whether this protein is a component of chromatin or a nuclear matrix protein. Scaffold attachment factors are a specific subset of nuclear matrix proteins (NMP) that specifically bind to S/MAR. The encoded protein is thought to serve as a molecular base to assemble a 'transcriptosome complex' in the vicinity of actively transcribed genes. It is involved in the regulation of heat shock protein 27 transcription, can act as an estrogen receptor co-repressor and is a candidate for breast tumorigenesis. This gene is arranged head-to-head with a similar gene whose product has the same functions. Multiple transcript variants encoding different isoforms have been found for this gene.

Alias Symbols: SAFB, HAP, HET, SAFB1,

Protein Interaction Partner: SUMO3, STAU1, UBC, LGR4, SUMO1, EED, rev, TP63, IL7R, CSNK2A1, MAP1LC3A, TP53BP1, TRMT112, TMOD2, RBMX, NCSTN, ACIN1, SMU1, U2AF2, CPSF6, GCN1L1, UTP14A, USP39, SAP18, VTN, U2AF1, TPBG, SURF4, SON, SRSF7, PRKAR1A, ABCC1, LAMP2, SEPT7, AK2, ACAT1, ZC3H18,

Protein Size: 848

Gen-ID: 6294

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway