SAFB Antikörper (N-Term)

Produktnummer ABIN5515129

Produktdetails anti-SAFB Antikörper

Target: SAFB (Scaffold Attachment Factor B (SAFB))

Bindungsspezifität: N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SAFB Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: MAETLSGLGD SGAAGAAALS SASSETGTRR LSDLRVIDLR AELRKRNVDS

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 93%, Rat: 100%

Aufreinigung: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SAFB

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu SAFB

Target: SAFB (Scaffold Attachment Factor B (SAFB))

Andere Bezeichnung: SAFB (SAFB Produkte)

Synonyme: HAP antikoerper, HET antikoerper, SAF-B1 antikoerper, SAFB1 antikoerper, 3110021E02Rik antikoerper, 5330423C17Rik antikoerper, AU018122 antikoerper, D18386 antikoerper, E130307D12 antikoerper, zgc:55387 antikoerper, wu:fb40a03 antikoerper, wu:fd42g06 antikoerper, SAFB2 antikoerper, SAFB antikoerper, scaffold attachment factor B antikoerper, scaffold attachment factor B S homeolog antikoerper, SAFB-like transcription modulator antikoerper, Scaffold attachment factor B antikoerper, SAFB antikoerper, Safb antikoerper, safb antikoerper, safb.S antikoerper, LOC5570070 antikoerper, CpipJ_CPIJ017179 antikoerper, Bm1_49330 antikoerper, LOAG_00080 antikoerper

Hintergrund: This gene encodes a DNA-binding protein which has high specificity for scaffold or matrix attachment region DNA elements(S/MAR DNA). This protein is thought to be involved in attachingthe base of chromatin loops to the nuclear matrix but there isconflicting evidence as to whether this protein is a component of chromatin or a nuclear matrix protein. Scaffold attachment factorsare a specific subset of nuclear matrix proteins (NMP) that specifically bind to S/MAR. The encoded protein is thought to serveas a molecular base to assemble a 'transcriptosome complex' in thevicinity of actively transcribed genes. It is involved in theregulation of heat shock protein 27 transcription, can act as anestrogen receptor co-repressor and is a candidate for breast tumorigenesis. This gene is arranged head-to-head with a similar gene whose product has the same functions. Multiple transcriptvariants encoding different isoforms have been found for this gene.

Alias Symbols: HAP, HET, SAF-B, SAFB1, SAB-B1, SAF-B1

Protein Interaction Partner: SUMO3, STAU1, UBC, LGR4, SUMO1, EED, rev, TP63, IL7R, CSNK2A1, MAP1LC3A, TP53BP1, TRMT112, TMOD2, RBMX, NCSTN, ACIN1, SMU1, U2AF2, CPSF6, GCN1L1, UTP14A, USP39, SAP18, VTN, U2AF1, TPBG, SURF4, SON, SRSF7, PRKAR1A, ABCC1, LAMP2, SEPT7, AK2, ACAT1, ZC3H18,

Protein Size: 848

Gen-ID: 6294

NCBI Accession: NM_002967, NP_002958

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway