PMS1 Antikörper (Middle Region)

Produktnummer ABIN5515042

Produktdetails anti-PMS1 Antikörper

Target: PMS1 (PMS1 Postmeiotic Segregation Increased 1 (S. Cerevisiae) (PMS1))

Bindungsspezifität: Middle Region

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PMS1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: PFQNDMHNDE SGKNTDDCLN HQISIGDFGY GHCSSEISNI DKNTKNAFQD

Produktmerkmale: This is a rabbit polyclonal antibody against PMS1. It was validated on Western Blot.

Aufreinigung: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human PMS1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu PMS1

Target: PMS1 (PMS1 Postmeiotic Segregation Increased 1 (S. Cerevisiae) (PMS1))

Andere Bezeichnung: PMS1 (PMS1 Produkte)

Synonyme: PMSL1 antikoerper, si:dz72b14.2 antikoerper, si:dz164h20.2 antikoerper, PMS1 antikoerper, DKFZp468M105 antikoerper, pms1 antikoerper, HNPCC3 antikoerper, hPMS1 antikoerper, PMS1 homolog 1, mismatch repair system component antikoerper, PMS1 homolog 1, mismatch repair system component S homeolog antikoerper, PMS1 antikoerper, Pms1 antikoerper, pms1 antikoerper, pms1.S antikoerper

Hintergrund: This gene encodes a protein belonging to the DNA mismatch repair mutL/hexB family. This protein is thought to be involved in the repair of DNA mismatches, and it can form heterodimers with MLH1, a known DNA mismatch repair protein. Mutations in this gene cause hereditary nonpolyposis colorectal cancer type 3 (HNPCC3) either alone or in combination with mutations in other genes involved in the HNPCC phenotype, which is also known as Lynch syndrome.

Alias Symbols: MLH2, PMSL1, hPMS1, HNPCC3

Protein Interaction Partner: UBC, MSH6, MSH2, MLH1, FAN1, USP5, TOP1, SBF1, RFC4, RFC2, RFC1, REV3L, RANGAP1, PSMC1, PPP2R1A, PMS1, PIK3C2A, PGK1, NONO, MOV10, MCM6, IPO5, KPNA2, CYLD, CDK9, CDC5L, CCNT1, BRCA2, ATR, HELB, PSD2, BRIP1, SBF2, MMS19, RNF123, RNF20, IPO9, UBR5, AKAP9, R

Protein Size: 932

Gen-ID: 5378

NCBI Accession: NM_000534, NP_000525

UniProt: P54277