NCK2 Antikörper (Middle Region)

Produktnummer ABIN5514984

Produktdetails anti-NCK2 Antikörper

Target: NCK2 (NCK Adaptor Protein 2 (NCK2))

Bindungsspezifität: Middle Region

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NCK2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: LGLGKTRRKT SARDASPTPS TDAEYPANGS GADRIYDLNI PAFVKFAYVA

Aufreinigung: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human NCK2

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu NCK2

Target: NCK2 (NCK Adaptor Protein 2 (NCK2))

Andere Bezeichnung: NCK2 (NCK2 Produkte)

Synonyme: GRB4 antikoerper, NCKbeta antikoerper, NCK2 antikoerper, 4833426I10Rik antikoerper, Grb4 antikoerper, Nck-2 antikoerper, Nck2 antikoerper, zgc:55283 antikoerper, fd20h08 antikoerper, im:7147817 antikoerper, si:ch211-147g19.3 antikoerper, wu:fd20h08 antikoerper, zgc:92024 antikoerper, NCK adaptor protein 2 antikoerper, cytoplasmic protein NCK2-like antikoerper, non-catalytic region of tyrosine kinase adaptor protein 2 antikoerper, NCK adaptor protein 2a antikoerper, NCK adaptor protein 2b antikoerper, NCK2 antikoerper, Nck2 antikoerper, LOC100227348 antikoerper, nck2a antikoerper, nck2b antikoerper

Hintergrund: This gene encodes a member of the NCK family of adaptor proteins. The protein contains three SH3 domains and one SH2 domain. The protein has no known catalytic function but has been shown to bind and recruit various proteins involved in the regulation of receptor protein tyrosine kinases. It is through these regulatory activities that this protein is believed to be involved in cytoskeletal reorganization. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Alias Symbols: GRB4, NCKbeta,

Protein Size: 380

Gen-ID: 8440

NCBI Accession: NM_001004720, NP_001004720

UniProt: O43639

Pathways: EGFR Signaling Pathway, Regulation of Actin Filament Polymerization