HTRA2 Antikörper (Middle Region)

Produktnummer ABIN5514857

Produktdetails anti-HTRA2 Antikörper

Target: HTRA2 (HtrA Serine Peptidase 2 (HTRA2))

Bindungsspezifität: Middle Region

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HTRA2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: TMKVTAGISF AIPSDRLREF LHRGEKKNSS SGISGSQRRY IGVMMLTLSP

Aufreinigung: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human HTRA2

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 23 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu HTRA2

Target: HTRA2 (HtrA Serine Peptidase 2 (HTRA2))

Andere Bezeichnung: HTRA2 (HTRA2 Produkte)

Synonyme: CG8464 antikoerper, DmHtrA2 antikoerper, Dmel\\CG8464 antikoerper, HtrA2/Omi antikoerper, Omi antikoerper, dOmi antikoerper, domi antikoerper, htrA2 antikoerper, omi antikoerper, HTRA2 antikoerper, PRSS25 antikoerper, OMI antikoerper, PARK13 antikoerper, AI481710 antikoerper, Prss25 antikoerper, mnd2 antikoerper, HTRA2-related serine protease antikoerper, HtrA serine peptidase 2 antikoerper, HtrA2 antikoerper, HTRA2 antikoerper, htra2 antikoerper, Htra2 antikoerper

Hintergrund: This gene encodes a serine protease. The protein has been localized in the endoplasmic reticulum and interacts with an alternatively spliced form of mitogen-activated protein kinase 14. The protein has also been localized to the mitochondria with release to the cytosol following apoptotic stimulus. The protein is thought to induce apoptosis by binding the apoptosis inhibitory protein baculoviral IAP repeat-containing 4. Nuclear localization of this protein has also been observed. Alternate splicing of this gene results in two transcript variants encoding different isoforms. Additional transcript variants have been described, but their full-length sequences have not been determined.

Alias Symbols: OMI, PARK13, PRSS25

Protein Size: 361

Gen-ID: 27429

NCBI Accession: NM_013247, NP_037379

Pathways: Positive Regulation of Endopeptidase Activity