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Desmocollin 3 Antikörper (Middle Region)

DSC3 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN5514719
  • Target Alle Desmocollin 3 (DSC3) Antikörper anzeigen
    Desmocollin 3 (DSC3)
    Bindungsspezifität
    • 9
    • 8
    • 8
    • 5
    • 2
    • 2
    • 1
    • 1
    Middle Region
    Reaktivität
    • 44
    • 32
    • 20
    • 5
    • 4
    • 1
    • 1
    • 1
    Human
    Wirt
    • 42
    • 2
    • 1
    • 1
    Kaninchen
    Klonalität
    • 44
    • 2
    Polyklonal
    Konjugat
    • 14
    • 5
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Desmocollin 3 Antikörper ist unkonjugiert
    Applikation
    • 41
    • 19
    • 13
    • 5
    • 4
    • 2
    • 1
    Western Blotting (WB)
    Sequenz
    IKENLAVGSK INGYKAYDPE NRNGNGLRYK KLHDPKGWIT IDEISGSIIT
    Aufreinigung
    Affinity purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human DSC3
    Top Product
    Discover our top product DSC3 Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    Desmocollin 3 (DSC3)
    Andere Bezeichnung
    DSC3 (DSC3 Produkte)
    Synonyme
    CDHF3 antikoerper, DSC antikoerper, DSC1 antikoerper, DSC2 antikoerper, DSC4 antikoerper, HT-CP antikoerper, 5430426I24Rik antikoerper, MGC85083 antikoerper, desmocollin 3 antikoerper, desmocollin 3 S homeolog antikoerper, DSC3 antikoerper, Dsc3 antikoerper, dsc3.S antikoerper, dsc3 antikoerper
    Hintergrund
    The protein encoded by this gene is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. These desmosomal family members, along with the desmogleins, are found primarily in epithelial cells where they constitute the adhesive proteins of the desmosome cell-cell junction and are required for cell adhesion and desmosome formation. The desmosomal family members are arranged in two clusters on chromosome 18, occupying less than 650 kb combined. Mutations in this gene are a cause of hypotrichosis and recurrent skin vesicles disorder. The protein can act as an autoantigen in pemphigus diseases, and it is also considered to be a biomarker for some cancers. Alternative splicing of this gene results in multiple transcript variants.

    Alias Symbols: DSC, DSC1, DSC2, DSC4, CDHF3, HT-CP,

    Protein Size: 839
    Gen-ID
    1825
    NCBI Accession
    NM_001941, NP_001932
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