Desmocollin 3 Antikörper (Middle Region)

Produktnummer ABIN5514719

Produktdetails anti-Desmocollin 3 Antikörper

Target: Desmocollin 3 (DSC3)

Bindungsspezifität: Middle Region

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Desmocollin 3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: IKENLAVGSK INGYKAYDPE NRNGNGLRYK KLHDPKGWIT IDEISGSIIT

Aufreinigung: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human DSC3

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu Desmocollin 3

Target: Desmocollin 3 (DSC3)

Andere Bezeichnung: DSC3 (DSC3 Produkte)

Synonyme: CDHF3 antikoerper, DSC antikoerper, DSC1 antikoerper, DSC2 antikoerper, DSC4 antikoerper, HT-CP antikoerper, 5430426I24Rik antikoerper, MGC85083 antikoerper, desmocollin 3 antikoerper, desmocollin 3 S homeolog antikoerper, DSC3 antikoerper, Dsc3 antikoerper, dsc3.S antikoerper, dsc3 antikoerper

Hintergrund: The protein encoded by this gene is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. These desmosomal family members, along with the desmogleins, are found primarily in epithelial cells where they constitute the adhesive proteins of the desmosome cell-cell junction and are required for cell adhesion and desmosome formation. The desmosomal family members are arranged in two clusters on chromosome 18, occupying less than 650 kb combined. Mutations in this gene are a cause of hypotrichosis and recurrent skin vesicles disorder. The protein can act as an autoantigen in pemphigus diseases, and it is also considered to be a biomarker for some cancers. Alternative splicing of this gene results in multiple transcript variants.

Alias Symbols: DSC, DSC1, DSC2, DSC4, CDHF3, HT-CP,

Protein Size: 839

Gen-ID: 1825

NCBI Accession: NM_001941, NP_001932