DGCR8 Antikörper (Middle Region)

Produktnummer ABIN5514704

Produktdetails anti-DGCR8 Antikörper

Target: DGCR8 (DiGeorge Syndrome Critical Region Gene 8 (DGCR8))

Bindungsspezifität: Middle Region

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DGCR8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: TEEKYGGDSD HPSDGETSVQ PMMTKIKTVL KSRGRPPTEP LPDGWIMTFH

Produktmerkmale: This is a rabbit polyclonal antibody against DGCR8. It was validated on Western Blot.

Aufreinigung: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human DGCR8

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu DGCR8

Target: DGCR8 (DiGeorge Syndrome Critical Region Gene 8 (DGCR8))

Andere Bezeichnung: DGCR8 (DGCR8 Produkte)

Synonyme: MGC78846 antikoerper, DGCR8 antikoerper, gy1 antikoerper, dgcrk6 antikoerper, C22orf12 antikoerper, DGCRK6 antikoerper, Gy1 antikoerper, pasha antikoerper, D16H22S1742E antikoerper, D16H22S788E antikoerper, D16Wis2 antikoerper, N41 antikoerper, Vo59c07 antikoerper, si:ch211-106a19.4 antikoerper, wu:fc23f08 antikoerper, wu:fc38f06 antikoerper, DGCR8 microprocessor complex subunit L homeolog antikoerper, DiGeorge syndrome critical region gene 8 antikoerper, DGCR8 microprocessor complex subunit antikoerper, DGCR8, microprocessor complex subunit antikoerper, microRNA 3618 antikoerper, dgcr8.L antikoerper, DGCR8 antikoerper, dgcr8 antikoerper, Dgcr8 antikoerper, MIR3618 antikoerper

Hintergrund: This gene encodes a subunit of the microprocessor complex which mediates the biogenesis of microRNAs from the primary microRNA transcript. The encoded protein is a double-stranded RNA binding protein that functions as the non-catalytic subunit of the microprocessor complex. This protein is required for binding the double-stranded RNA substrate and facilitates cleavage of the RNA by the ribonuclease III protein, Drosha. Alternate splicing results in multiple transcript variants.

Alias Symbols: DGCR8, C22orf12, DGCRK6, LP4941,

Protein Interaction Partner: MEOX2, PYCRL, DROSHA, RAE1, MAPK1, PRMT1, ERH, CDKN2A, BMI1, SRPK2, SRPK1, CDT1, NAT10, PLEK2, RPRD2, MAPRE2, PRPF4, FLII, APP, CUL3, DDX17, HNRNPR, NCL, ILF3, HSPA8, HSPA5, HNRNPU, HNRNPH1, FUS, DHX9, DDX5,

Protein Size: 773

Gen-ID: 54487

NCBI Accession: NP_073557

UniProt: Q8WYQ5

Pathways: Regulatorische RNA Pathways