CREM Antikörper (C-Term)

Produktnummer ABIN5514597

Produktdetails anti-CREM Antikörper

Target: CREM (CAMP Responsive Element Modulator (CREM))

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CREM Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: LHSPQQLAEE ATRKRELRLM KNREAAKECR RRKKEYVKCL ESRVAVLEVQ

Produktmerkmale: This is a rabbit polyclonal antibody against CREM. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human CREM

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu CREM

Target: CREM (CAMP Responsive Element Modulator (CREM))

Andere Bezeichnung: CREM (CREM Produkte)

Synonyme: CREM antikoerper, ICER antikoerper, CREM-2 antikoerper, hCREM-2 antikoerper, ICERI antikoerper, Icer antikoerper, cAMP responsive element modulator antikoerper, CREM antikoerper, Crem antikoerper

Hintergrund: This gene encodes a bZIP transcription factor that binds to the cAMP responsive element found in many viral and cellular promoters. It is an important component of cAMP-mediated signal transduction during the spermatogenetic cycle, as well as other complex processes. Alternative promoter and translation initiation site usage allows this gene to exert spatial and temporal specificity to cAMP responsiveness. Multiple alternatively spliced transcript variants encoding several different isoforms have been found for this gene, with some of them functioning as activators and some as repressors of transcription.

Alias Symbols: CREM,

Protein Interaction Partner: CREB1, PIAS3, CASP8AP2, UBE2I, UBC, SP100, ATXN1, EMP3, HHV8GK18_gp81, MAPK3, CREB3L4, HDAC1, CREB3L1, TAF4, CAMK2D, GSK3A, FHL5, GSK3B, KCNIP3, CAMK2G, PRKACA, CSNK1A1, CREBBP, TBP, PRKCA, SPI1, CREM, ATF1, CDC34, CDK1, CSNK2A2, CSNK2A1, CD34,

Protein Size: 221

Gen-ID: 1390

Pathways: Retinoic Acid Receptor Signaling Pathway