BCAR1 Antikörper (pTyr762)

Produktnummer ABIN548481

Produktdetails anti-BCAR1 Antikörper

Target: BCAR1 (Breast Cancer Anti-Estrogen Resistance 1 (BCAR1))

Bindungsspezifität: pTyr762

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BCAR1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunoprecipitation (IP)

Verwendungszweck: Rabbit polyclonal antibody raised against synthetic phosphopeptide of Bcar1.

Spezifität: This rat sequence is the same as Tyr-664 in human p130 Cas and Tyr-668 in mouse p130 Cas.

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Antibody Reactive Against Synthetic Peptide.

Immunogen: Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding Y762 of rat Bcar1.

Anwendungsinformationen

Applikationshinweise: ELISA (1:2000)
Immunoprecipitation (5-10 µL)
Western Blot (1:2000)
The optimal working dilution should be determined by the end user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In PBS (50 % glycerol, 1 mg/mL BSA, 0.05 % sodium azide)

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C.
Aliquot to avoid repeated freezing and thawing.

Referenzen für anti-BCAR1 Antikörper (ABIN548481)

Shin, Dise, Schneider-Mergener, Ritchie, Kilkenny, Hanks: "Subsets of the major tyrosine phosphorylation sites in Crk-associated substrate (CAS) are sufficient to promote cell migration." in: The Journal of biological chemistry, Vol. 279, Issue 37, pp. 38331-7, (2004) (PubMed).

Hoon Kim, Jeon Choi, Kook, Kim, Keun Song: "Phosphorylation-dependent cleavage of p130cas in apoptotic rat-1 cells." in: Biochemical and biophysical research communications, Vol. 300, Issue 1, pp. 141-8, (2002) (PubMed).

Pellicena, Miller: "Processive phosphorylation of p130Cas by Src depends on SH3-polyproline interactions." in: The Journal of biological chemistry, Vol. 276, Issue 30, pp. 28190-6, (2001) (PubMed).

Details zu BCAR1

Target: BCAR1 (Breast Cancer Anti-Estrogen Resistance 1 (BCAR1))

Andere Bezeichnung: BCAR1 / CRKAS (BCAR1 Produkte)

Synonyme: CAS antikoerper, CAS1 antikoerper, CASS1 antikoerper, CRKAS antikoerper, P130Cas antikoerper, AI385681 antikoerper, Cas antikoerper, Crkas antikoerper, P130CAS antikoerper, MGC68466 antikoerper, cas antikoerper, p130cas antikoerper, BCAR1 antikoerper, fc17f11 antikoerper, wu:fc17f11 antikoerper, zgc:175192 antikoerper, BCAR1, Cas family scaffolding protein antikoerper, breast cancer anti-estrogen resistance 1 antikoerper, breast cancer anti-estrogen resistance 1 L homeolog antikoerper, breast cancer anti-estrogen resistance protein 1 antikoerper, BCAR1 antikoerper, Bcar1 antikoerper, bcar1.L antikoerper, bcar1 antikoerper, LOC100435586 antikoerper

Gen-ID: 25414

Pathways: EGFR Signaling Pathway, Neurotrophin Signalübertragung, CXCR4-mediated Signaling Events, Platelet-derived growth Factor Receptor Signaling