PML Antikörper

Produktnummer ABIN545269

Produktdetails anti-PML Antikörper

Target: PML (Promyelocytic Leukemia (PML))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PML Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Verwendungszweck: Rabbit polyclonal antibody raised against synthetic peptide of PML.

Sequenz: PRKVIKMESE EGKEA

Spezifität: This antibody recognize synthetic peptide (PRKVIKMESEEGKEA) containing a predicted sumoylation site of human PML.

Kreuzreaktivität: Human

Immunogen: A synthetic peptide (conjugated with KLH) corresponding to human PML.

Anwendungsinformationen

Applikationshinweise: ELISA (1:1000)
Western Blot (1:100-500)
Immunohistochemistry (1:50-100)
The optimal working dilution should be determined by the end user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In PBS (0.09 % sodium azide)

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.

Referenzen für anti-PML Antikörper (ABIN545269)

Kawai, Akira, Reed: "ZIP kinase triggers apoptosis from nuclear PML oncogenic domains." in: Molecular and cellular biology, Vol. 23, Issue 17, pp. 6174-86, (2003) (PubMed).

Favre, Butticaz, Stevenson, Jongeneel, Telenti: "High frequency of alternative splicing of human genes participating in the HIV-1 life cycle: a model using TSG101, betaTrCP, PPIA, INI1, NAF1, and PML." in: Journal of acquired immune deficiency syndromes (1999), Vol. 34, Issue 2, pp. 127-33, (2003) (PubMed).

Puccetti, Beissert, Güller, Li, Hoelzer, Ottmann, Ruthardt: "Leukemia-associated translocation products able to activate RAS modify PML and render cells sensitive to arsenic-induced apoptosis." in: Oncogene, Vol. 22, Issue 44, pp. 6900-8, (2003) (PubMed).

Details zu PML

Target: PML (Promyelocytic Leukemia (PML))

Andere Bezeichnung: PML / RNF71 (PML Produkte)

Synonyme: MYL antikoerper, PP8675 antikoerper, RNF71 antikoerper, TRIM19 antikoerper, 1200009E24Rik antikoerper, AI661194 antikoerper, Trim19 antikoerper, RGD1562602 antikoerper, PML antikoerper, promyelocytic leukemia antikoerper, PML antikoerper, Pml antikoerper

Gen-ID: 5371

Pathways: p53 Signalweg, Retinoic Acid Receptor Signaling Pathway, Maintenance of Protein Location, Positive Regulation of Endopeptidase Activity, Protein targeting to Nucleus