Histone Cluster 2, H3c (HIST2H3C) (Lys27) Antikörper

Produktnummer ABIN540989

Produktdetails

Target: Histone Cluster 2, H3c (HIST2H3C)

Bindungsspezifität: Lys27

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Chromatin Immunoprecipitation (ChIP), Immunofluorescence (IF)

Verwendungszweck: Rabbit polyclonal antibody raised against synthetic peptide of HIST2H3C.

Spezifität: This antibody only recognizes ~17 KDa of Dimethylated HIST2H3C. It does not cross react to non-methylated H3 or mono-, Tri-methylated Histone H3.

Kreuzreaktivität: Huhn, Rind (Kuh), Human, Maus, Ratte

Produktmerkmale: Antibody Reactive Against Synthetic Peptide.

Immunogen: A synthetic peptide corresponding to dimethyl lysine 27 of human HIST2H3C.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western Blot (0.1-1 μg/mL)
ELISA (0.01-0.1 μg/mL)
Immunoprecipitation (2-5 μg/mL)
Immunohistochemistry (1:100)
The optimal working dilution should be determined by the end user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In TBS, pH 7.2 (BSA, 10 % Proclin300)

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C. For long term storage store at -20°C or lower.
Aliquot to avoid repeated freezing and thawing.

Referenzen

Seward, Cubberley, Kim, Schonewald, Zhang, Tripet, Bentley: "Demethylation of trimethylated histone H3 Lys4 in vivo by JARID1 JmjC proteins." in: Nature structural & molecular biology, Vol. 14, Issue 3, pp. 240-2, (2007) (PubMed).

Vakoc, Mandat, Olenchock, Blobel: "Histone H3 lysine 9 methylation and HP1gamma are associated with transcription elongation through mammalian chromatin." in: Molecular cell, Vol. 19, Issue 3, pp. 381-91, (2005) (PubMed).

Antigendetails

Target: Histone Cluster 2, H3c (HIST2H3C)

Andere Bezeichnung: HIST2H3C (HIST2H3C Produkte)

Synonyme: H3 antikoerper, H3.2 antikoerper, H3/M antikoerper, H3F2 antikoerper, H3FM antikoerper, H3FN antikoerper, histone cluster 2 H3 family member c antikoerper, HIST2H3C antikoerper

Gen-ID: 126961