GRIN2B Antikörper (Tyr1474)

Produktnummer ABIN540488

Produktdetails anti-GRIN2B Antikörper

Target: GRIN2B (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2B (GRIN2B))

Bindungsspezifität: Tyr1474

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GRIN2B Antikörper ist unkonjugiert

Applikation: Immunofluorescence (IF)

Verwendungszweck: Rabbit polyclonal antibody raised against synthetic peptide of GRIN2B.

Sequenz: HVYEK

Spezifität: NMDAR2B (Ab-1472) antibody detects endogenous levels of total NMDAR2B protein.

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Antibody Reactive Against Synthetic Peptide.

Immunogen: A synthetic peptide (conjugated with KLH) corresponding to residues surrounding Y1474 of human GRIN2B.

Anwendungsinformationen

Applikationshinweise: Immunofluorescence (1:100-1:200)
The optimal working dilution should be determined by the end user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: In PBS (without Mg²⁺ and Ca²⁺), 150 mM NaCl, pH 7.4 (50 % glycerol, 0.02 % sodium azide)

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C.
Aliquot to avoid repeated freezing and thawing.

Referenzen für anti-GRIN2B Antikörper (ABIN540488)

Chazot: "The NMDA receptor NR2B subunit: a valid therapeutic target for multiple CNS pathologies." in: Current medicinal chemistry, Vol. 11, Issue 3, pp. 389-96, (2004) (PubMed).

Kakegawa, Tsuzuki, Iino, Ozawa: "Functional NMDA receptor channels generated by NMDAR2B gene transfer in rat cerebellar Purkinje cells." in: The European journal of neuroscience, Vol. 17, Issue 4, pp. 887-91, (2003) (PubMed).

Babb, Ying, Mikuni, Nishiyama, Drazba, Bingaman, Wyllie, Wylie, Yacubova: "Brain plasticity and cellular mechanisms of epileptogenesis in human and experimental cortical dysplasia." in: Epilepsia, Vol. 41 Suppl 6, pp. S76-81, (2000) (PubMed).

Details zu GRIN2B

Target: GRIN2B (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2B (GRIN2B))

Andere Bezeichnung: NMDAR2B (GRIN2B Produkte)

Synonyme: NMDAR2B antikoerper, GluN2B antikoerper, MRD6 antikoerper, NR2B antikoerper, hNR3 antikoerper, nmdar2b antikoerper, nr2b antikoerper, AW490526 antikoerper, Nmdar2b antikoerper, glutamate ionotropic receptor NMDA type subunit 2B antikoerper, glutamate receptor, ionotropic, N-methyl D-aspartate 2B L homeolog antikoerper, glutamate receptor, ionotropic, NMDA2B (epsilon 2) antikoerper, GRIN2B antikoerper, Grin2b antikoerper, grin2b.L antikoerper

Gen-ID: 2904

Pathways: Response to Growth Hormone Stimulus, Synaptic Membrane, Feeding Behaviour, Regulation of long-term Neuronal Synaptic Plasticity