MARK2 Antikörper (pThr595)

Produktnummer ABIN538475

Produktdetails anti-MARK2 Antikörper

Target: MARK2 (MAP/microtubule Affinity-Regulating Kinase 2 (MARK2))

Bindungsspezifität: pThr595

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MARK2 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunofluorescence (IF)

Verwendungszweck: Rabbit polyclonal antibody raised against synthetic phosphopeptide of MARK2.

Spezifität: Reactivity occurs against human MARK2 pT595 protein and This antibody is specific to the phosphorylated form of the protein. Reactivity with non-phosphorylated human MARK2 is minimal by ELISA. Expect at least partial reactivity with other isoforms of MARK. The immunogen sequence is present in all forms identified to date and localizes to T595 on MARK2, T587 on MARK3, T591 on MARK1 and T568 on MARK4.

Kreuzreaktivität: Rind (Kuh), Hund, Human, Maus, Ratte

Produktmerkmale: Antibody Reactive Against Synthetic Peptide.

Immunogen: Synthetic phosphopeptide corresponding to residues surrounding T595 of human MARK2.

Anwendungsinformationen

Applikationshinweise: ELISA (1:1000-1:3000)
Western Blot (1:250-1:1000)
The optimal working dilution should be determined by the end user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 20 mM KH₂PO₄, 150 mM NaCl, pH 7.2 (0.01 % sodium azide)

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.

Referenzen für anti-MARK2 Antikörper (ABIN538475)

Hurov, Watkins, Piwnica-Worms: "Atypical PKC phosphorylates PAR-1 kinases to regulate localization and activity." in: Current biology : CB, Vol. 14, Issue 8, pp. 736-41, (2004) (PubMed).

Hueso, Beltran, Moreso, Ciriero, Fulladosa, Grinyó, Serón, Navarro et al.: "Splicing alterations in human renal allografts: detection of a new splice variant of protein kinase Par1/Emk1 whose expression is associated with an increase of inflammation in protocol biopsies of ..." in: Biochimica et biophysica acta, Vol. 1689, Issue 1, pp. 58-65, (2004) (PubMed).

Sun, Lu, Feng, Reinhard, Jan, Fantl, Williams: "PAR-1 is a Dishevelled-associated kinase and a positive regulator of Wnt signalling." in: Nature cell biology, Vol. 3, Issue 7, pp. 628-36, (2001) (PubMed).

Details zu MARK2

Target: MARK2 (MAP/microtubule Affinity-Regulating Kinase 2 (MARK2))

Andere Bezeichnung: MARK2 (MARK2 Produkte)

Synonyme: EMK-1 antikoerper, EMK1 antikoerper, PAR-1 antikoerper, Par-1b antikoerper, Par1b antikoerper, AU024026 antikoerper, Emk antikoerper, Par-1 antikoerper, mKIAA4207 antikoerper, microtubule affinity regulating kinase 2 antikoerper, MAP/microtubule affinity regulating kinase 2 antikoerper, MARK2 antikoerper, Mark2 antikoerper

Gen-ID: 2011

Pathways: SARS-CoV-2 Protein Interaktom, Phosphorylierungen bei SARS-CoV-2 Infektion