Mitofusin 1 (MFN1) (AA 1-741), (full length) Antikörper

Details zu Produkt Nr. ABIN527615, Anbieter: Anmelden zum Anzeigen
Antigen
  • mfn1
  • zgc:66150
  • mitofusin-1
  • MFN1
  • MFN2
  • hfzo1
  • hfzo2
  • 2310002F04Rik
  • 6330416C07Rik
  • D3Ertd265e
  • HR2
  • mKIAA4032
  • Fzo1b
  • mitofusin 1b
  • mitofusin 1
  • mitofusin 1 S homeolog
  • mfn1b
  • MFN1
  • mfn1.S
  • mfn1
  • Mfn1
Epitop
AA 1-741, full length
22
16
13
10
8
8
8
8
3
3
2
2
2
2
2
2
1
1
1
1
1
1
1
1
Reaktivität
Human
107
77
72
7
7
6
5
5
2
2
2
1
1
1
1
1
Wirt
Maus
82
35
13
2
Klonalität (Klon)
Monoklonal ()
Konjugat
Unkonjugiert
6
5
5
5
4
3
3
3
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
RNA Interference (RNAi), ELISA, Western Blotting (WB)
101
64
45
37
37
31
16
13
4
2
2
1
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Immunogen MFN1 (AAH40557, 1 a.a. ~ 741 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Immunogen sequence: MAEPVSPLKH FVLAKKAITA IFDQLLEFVT EGSHFVEATY KNPELDRIAT EDDLVEMQGY KDKLSIIGEV LSRRHMKVAF FGRTSSGKSS VINAMLWDKV LPSGIGHITN CFLSVEGTDG DKAYLMTEGS DEKKSVKTVN QLAHALHMDK DLKAGCLVRV FWPKAKCALL RDDLVLVDSP GTDVTTELDS WIDKFCLDAD VFVLVANSES TLMNTEKHFF HKVNERLSKP NIFILNNRWD ASASEPEYME DVRRQHMERC LHFLVEELKV VNALEAQNRI FFVSAKEVLS ARKQKAQGMP ESGVALAEGF HARLQEFQNF EQIFEECISQ SAVKTKFEQH TIRAKQILAT VKNIMDSVNL AAEDKRHYSV EEREDQIDRL DFIRNQMNLL TLDVKKKIKE VTEEVANKVS CAMTDEICRL SVLVDEFCSE FHPNPDVLKI YKSELNKHIE DGMGRNLADR CTDEVNALVL QTQQEIIENL KPLLPAGIQD KLHTLIPCKK FDLSYNLNYH KLCSDFQEDI VFRFSLGWSS LVHRFLGPRN AQRVLLGLSE PIFQLPRSLA STPTAPTTPA TPDNASQEEL MITLVTGLAS VTSRTSMGII IVGGVIWKTI GWKLLSVSLT MYGALYLYER LSWTTHAKER AFKQQFVNYA TEKLRMIVSS TSANCSHQVK QQIATTFARL CQQVDITQKQ LEEEIARLPK EIDQLEKIQN NSKLLRNKAV QLENELENFT KQFLPSSNEE S
Klon 3C9
Isotyp IgG2a kappa
Kreuzreaktivität Human
Andere Bezeichnung MFN1 (MFN1 Antibody Abstract)
Hintergrund Full Gene Name: mitofusin 1
Synonyms: DKFZp762F247,FLJ20693,MGC41806,hfzo1,hfzo2
Gen-ID 55669
Applikations-hinweise Optimal working dilution should be determined by the investigator.
Kommentare

Product Quality tested by: Antibody Reactive Against Recombinant Protein.

Beschränkungen Nur für Forschungszwecke einsetzbar
Buffer In 1x PBS, pH 7.4
Handhabung Aliquot to avoid repeated freezing and thawing.
Lagerung -20 °C
Informationen zur Lagerung Store at -20 °C or lower. Aliquot to avoid repeated freezing and thawing.
Bilder des Herstellers
Western Blotting (WB) image for anti-Mitofusin 1 (MFN1) (AA 1-741), (full length) antibody (ABIN527615) MFN1 monoclonal antibody (M04), clone 3C9 Western Blot analysis of MFN1 expression in...
Western Blotting (WB) image for anti-Mitofusin 1 (MFN1) (AA 1-741), (full length) antibody (ABIN527615) Western blot analysis of MFN1 over-expressed 293 cell line, cotransfected with MFN1 V...
Western Blotting (WB) image for anti-Mitofusin 1 (MFN1) (AA 1-741), (full length) antibody (ABIN527615) Western Blot analysis of MFN1 expression in transfected 293T cell line by MFN1 monocl...
ELISA image for anti-Mitofusin 1 (MFN1) (AA 1-741), (full length) antibody (ABIN527615) Detection limit for recombinant GST tagged MFN1 is 0.3 ng/ml as a capture antibody.
 image for anti-Mitofusin 1 (MFN1) (AA 1-741), (full length) antibody (ABIN527615) Western Blot detection against Immunogen (107.25 KDa) .
Western Blotting (WB) image for anti-Mitofusin 1 (MFN1) (AA 1-741), (full length) antibody (ABIN527615) MFN1 monoclonal antibody (M04), clone 3C9. Western Blot analysis of MFN1 expression i...
Produkt verwendet in: Chen, Chen, Wang, Tan, Zhu, Li, Han, Chen, Gao, Liu, Chen: "Mitophagy receptor FUNDC1 regulates mitochondrial dynamics and mitophagy." in: Autophagy, Vol. 12, Issue 4, pp. 689-702, 2016 (PubMed).

Baba, Kashiwagi, Arimitsu, Kogure, Edo, Maruyama, Nakao, Nakanishi, Kinoshita, Frohman, Yamamoto, Tani: "Phosphatidic acid (PA)-preferring phospholipase A1 regulates mitochondrial dynamics." in: The Journal of biological chemistry, Vol. 289, Issue 16, pp. 11497-511, 2014 (PubMed).

Yue, Chen, Liu, Yan, Chen, Feng, Yan, Wu, Du, Wang, Liu, Huang, Xia, Liu, Wang, Jin, Wang, Song, Hao, Chen: "A small natural molecule promotes mitochondrial fusion through inhibition of the deubiquitinase USP30." in: Cell research, Vol. 24, Issue 4, pp. 482-96, 2014 (PubMed).

Shiba-Fukushima, Inoshita, Hattori, Imai: "Lysine 63-linked polyubiquitination is dispensable for Parkin-mediated mitophagy." in: The Journal of biological chemistry, Vol. 289, Issue 48, pp. 33131-6, 2014 (PubMed).

Takamura, Koyama, Matsuzaki, Yamada, Hattori, Miyata, Takemoto, Tohyama, Katayama: "TRAP1 controls mitochondrial fusion/fission balance through Drp1 and Mff expression." in: PLoS ONE, Vol. 7, Issue 12, pp. e51912, 2013 (PubMed).

Goller, Seibold, Kremmer, Voos, Kolanus: "Atad3 function is essential for early post-implantation development in the mouse." in: PLoS ONE, Vol. 8, Issue 1, pp. e54799, 2013 (PubMed).

Russell, Lamon, Boon, Wada, Güller, Brown, Chibalin, Zierath, Snow, Stepto, Wadley, Akimoto: "Regulation of miRNAs in human skeletal muscle following acute endurance exercise and short-term endurance training." in: The Journal of physiology, Vol. 591, Issue Pt 18, pp. 4637-53, 2013 (PubMed).

Ban-Ishihara, Ishihara, Sasaki, Mihara, Ishihara: "Dynamics of nucleoid structure regulated by mitochondrial fission contributes to cristae reformation and release of cytochrome c." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, Issue 29, pp. 11863-8, 2013 (PubMed).

Fülöp, Rajki, Katona, Szanda, Spät: "Extramitochondrial OPA1 and adrenocortical function." in: Molecular and cellular endocrinology, Vol. 381, Issue 1-2, pp. 70-9, 2013 (PubMed).

Lin, Lai, Lin, Lin, Wang, Lin, Lee, Wang, Chen: "Suppressor of cytokine signaling 6 (SOCS6) promotes mitochondrial fission via regulating DRP1 translocation." in: Cell death and differentiation, Vol. 20, Issue 1, pp. 139-53, 2012 (PubMed).

Shiba-Fukushima, Imai, Yoshida, Ishihama, Kanao, Sato, Hattori: "PINK1-mediated phosphorylation of the Parkin ubiquitin-like domain primes mitochondrial translocation of Parkin and regulates mitophagy." in: Scientific reports, Vol. 2, pp. 1002, 2012 (PubMed).

Bui, Gilady, Fitzsimmons, Benson, Lynes, Gesson, Alto, Strack, Scott, Simmen: "Rab32 modulates apoptosis onset and mitochondria-associated membrane (MAM) properties." in: The Journal of biological chemistry, Vol. 285, Issue 41, pp. 31590-602, 2010 (PubMed).

Zanna, Ghelli, Porcelli, Karbowski, Youle, Schimpf, Wissinger, Pinti, Cossarizza, Vidoni, Valentino, Rugolo, Carelli: "OPA1 mutations associated with dominant optic atrophy impair oxidative phosphorylation and mitochondrial fusion." in: Brain : a journal of neurology, Vol. 131, Issue Pt 2, pp. 352-67, 2008 (PubMed).

Holloway, Perry, Thrush, Heigenhauser, Dyck, Bonen, Spriet: "PGC-1alpha's relationship with skeletal muscle palmitate oxidation is not present with obesity despite maintained PGC-1alpha and PGC-1beta protein." in: American journal of physiology. Endocrinology and metabolism, Vol. 294, Issue 6, pp. E1060-9, 2008 (PubMed).

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