IL-37 Antikörper

Produktnummer ABIN5027737

Produktdetails anti-IL-37 Antikörper

Target: IL-37 (IL37) (Interleukin 37 (IL37))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IL-37 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Protein A Chromatography

Immunogen: Full length recombinant IL-37 protein was used as the immunogen for this antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 2-4 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: PBS containing 0.05 % BSA, PH 7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Details zu IL-37

Target: IL-37 (IL37) (Interleukin 37 (IL37))

Andere Bezeichnung: IL-37 (IL37 Produkte)

Synonyme: FIL1 antikoerper, FIL1(ZETA) antikoerper, FIL1Z antikoerper, IL-1F7 antikoerper, IL-1H antikoerper, IL-1H4 antikoerper, IL-1RP1 antikoerper, IL-37 antikoerper, IL1F7 antikoerper, IL1H4 antikoerper, IL1RP1 antikoerper, interleukin 37 antikoerper, IL37 antikoerper

Hintergrund: IL-37 (Interleukin-37) is a member of IL-1 family and is primarily an anti-inflammatory cytokine, which reduces systemic and local inflammation. There are five different splice variants of IL-37 termed IL-37a-e, where Isoform IL-37b is the largest isoform. IL-37 has significant sequence similarity with IL-18 and highly expressed in inflammatory tissues, which inhibits the excessive inflammatory response. The expression is highly induced by several toll-like receptor (TLR) ligands and pro-inflammatory cytokines such as IL-1beta, TNF-alpha, IFN-gamma. IL-37 is a potent inhibitor of innate immunity by shifting the cytokine equilibrium away from excessive inflammation.

Molekulargewicht: 20 kDa

Gen-ID: 27178

UniProt: Q9NZH6