Napsin (AA 150-350) Antikörper

Produktnummer ABIN5027389

Produktdetails

Target: Napsin

Bindungsspezifität: AA 150-350

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Unkonjugiert

Applikation: Immunohistochemistry (IHC), Western Blotting (WB)

Aufreinigung: Protein G Chromatography

Immunogen: A partial length recombinant Napsin protein (amino acids 150-350) was used as the immunogen for this antibody

Klon: ABM4H60

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: WB: 0.5-1 μg/mL, IHC: 5-10 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: PBS containing 0.05 % BSA, PH 7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Antigendetails

Target: Napsin

Hintergrund: Napsin A, a human aspartic proteinase is found primarily in type II pneumocytes and alveolar macrophages and predominantly expressed in lung and kidney. It is a reliable marker for pulmonary adenocarcinoma and is expressed in a subset of ovarian clear cell carcinomas (O-CCCs), endometrial (EM) CCCs, and endometrioid carcinomas (EC). It is also useful in evaluating SH (Sclerosing hemangiomas) (23194051). Napsin A acts as an anti-apoptotic protein that promotes resistance to cisplatin by degradation of the tumor suppressor p53, which is regulator of the cell cycle and co-works with cyclin kinase inhibitors as p21 and p27.

Molekulargewicht: 44 kDa

Gen-ID: 9476

UniProt: O96009