beta Arrestin 1 Antikörper (AA 150-318)
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- Target Alle beta Arrestin 1 (ARRB1) Antikörper anzeigen
- beta Arrestin 1 (ARRB1) (Arrestin, beta 1 (ARRB1))
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Bindungsspezifität
- AA 150-318
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser beta Arrestin 1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Aufreinigung
- Protein A Chromatography
- Immunogen
- A partial length recombinant Beta-arrestin 1 protein (amino acids 150-318) was used as the immunogen for this antibody.
- Isotyp
- IgG
- Top Product
- Discover our top product ARRB1 Primärantikörper
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- Applikationshinweise
- WB: 2-4 μg/mL
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 0.5 mg/mL
- Buffer
- PBS containing 0.05 % BSA, PH 7.4
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
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- Target
- beta Arrestin 1 (ARRB1) (Arrestin, beta 1 (ARRB1))
- Andere Bezeichnung
- Beta-arrestin 1 (ARRB1 Produkte)
- Synonyme
- arrb1 antikoerper, MGC83787 antikoerper, arb1 antikoerper, arr1 antikoerper, barr1 antikoerper, betaarr1 antikoerper, 1200006I17Rik antikoerper, AW208571 antikoerper, G430100A01Rik antikoerper, ARB1 antikoerper, ARR1 antikoerper, BARRES antikoerper, arrestin beta 1 antikoerper, arrestin, beta 1 antikoerper, arrestin beta 1 L homeolog antikoerper, beta-arrestin 1 antikoerper, putative beta-arrestin 1 antikoerper, ARRB1 antikoerper, arrb1 antikoerper, arrb1.L antikoerper, CpipJ_CPIJ016988 antikoerper, CpipJ_CPIJ017114 antikoerper, Smp_122900 antikoerper, Smp_126080 antikoerper, Smp_176980 antikoerper, Smp_152290 antikoerper, Arrb1 antikoerper
- Hintergrund
- Beta-arrestin 1, a member of arrestin family, is a cofactor of beta-adrenergic receptor kinase (BARK) in beta-adrenergic receptor desensitization and resensitization process. Beta-arrestin 1 acts as endocytic adapter for internalization of many G-protein coupled receptors. Beta-arrestin 1 is also associated with many other cellular processes like ubiquitination and down-regulation of the insulin-like growth factor-1 receptor, synaptic transmission in photoreceptor cells, working as a scaffold protein in G-protein coupled receptor signaling pathways. Two isoforms of beta-arrestin 1 have been identified, isoform 1 (47 kDa) and isoform 2 (46 kDa). Beta-arrestin 1 is highly expressed in liver, kidney, lungs and testes.
- Molekulargewicht
- 47 kDa
- Gen-ID
- 408
- UniProt
- P49407
- Pathways
- Positive Regulation of Peptide Hormone Secretion, Nuclear Hormone Receptor Binding, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, Phototransduction
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