SH3RF2 Antikörper (Alexa Fluor 750)

Produktnummer ABIN5009926

Produktdetails anti-SH3RF2 Antikörper (Alexa Fluor 750)

Target: SH3RF2 (SH3 Domain Containing Ring Finger 2 (SH3RF2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SH3RF2 Antikörper ist konjugiert mit Alexa Fluor 750

Applikation: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human RNF158

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu SH3RF2

Target: SH3RF2 (SH3 Domain Containing Ring Finger 2 (SH3RF2))

Andere Bezeichnung: RNF158 (SH3RF2 Produkte)

Synonyme: MGC81405 antikoerper, SH3RF2 antikoerper, HEPP1 antikoerper, POSHER antikoerper, PPP1R39 antikoerper, RNF158 antikoerper, 2310046K19 antikoerper, 9130023G24Rik antikoerper, AI452083 antikoerper, Ppp1r39 antikoerper, Posh2 antikoerper, SH3 domain containing ring finger 2 antikoerper, SH3 domain containing ring finger 2 S homeolog antikoerper, SH3RF2 antikoerper, sh3rf2.S antikoerper, sh3rf2 antikoerper, Sh3rf2 antikoerper

Hintergrund:

Synonyms: Heart protein phosphatase 1-binding protein, HEPP1, Putative E3 ubiquitin protein ligase SH3RF2, Putative E3 ubiquitin-protein ligase SH3RF2, RING finger protein 158, SH3 domain containing RING finger protein 2, SH3 domain-containing RING finger protein 2, SH3R2_HUMAN, Sh3rf2.

Background: The RING-type zinc finger motif is present in a number of viral and eukaryotic proteins and is made of a conserved cysteine-rich domain that is able to bind two zinc atoms. Proteins that contain this conserved domain are generally involved in the ubiquitination pathway of protein degradation. SH3RF2 (SH3 domain containing ring finger 2), also known as RNF158, is a 729 amino acid protein with one RING-type zinc finger domain and three SH3 domains. Via its RING-type zinc finger domain, SH3RF2 binds an E2 ubiquitin-conjugating enzyme. This suggests that SH3RF2 functions as an E3 ubiquitin-protein ligase that accepts a ubiquitin residue from an E2 ubiquitin-conjugating enzyme and immediately transfers that residue to a protein that is targeted for degradation. Due to alternative splicing events, SH3RF2 is expressed as two different isoforms.

Gen-ID: 153769