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POMT1 Antikörper (AA 651-747) (AbBy Fluor® 750)

POMT1 Reaktivität: Human IF (cc), IF (p) Wirt: Kaninchen Polyclonal AbBy Fluor® 750
Produktnummer ABIN5009049
  • Target Alle POMT1 Antikörper anzeigen
    POMT1 (Protein-O-Mannosyltransferase 1 (POMT1))
    Bindungsspezifität
    • 14
    • 10
    • 10
    • 7
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 651-747
    Reaktivität
    • 46
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 47
    Kaninchen
    Klonalität
    • 47
    Polyklonal
    Konjugat
    • 16
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser POMT1 Antikörper ist konjugiert mit AbBy Fluor® 750
    Applikation
    • 27
    • 18
    • 16
    • 16
    • 12
    • 12
    • 7
    • 3
    • 2
    • 1
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Homologie
    Human,Mouse,Rat,Cow,Pig,Horse
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human POMT1
    Isotyp
    IgG
    Top Product
    Discover our top product POMT1 Primärantikörper
  • Applikationshinweise
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    POMT1 (Protein-O-Mannosyltransferase 1 (POMT1))
    Andere Bezeichnung
    POMT1 (POMT1 Produkte)
    Synonyme
    LGMD2K antikoerper, MDDGA1 antikoerper, MDDGB1 antikoerper, MDDGC1 antikoerper, RT antikoerper, AI505244 antikoerper, protein O-mannosyltransferase 1 antikoerper, protein-O-mannosyltransferase 1 antikoerper, POMT1 antikoerper, Pomt1 antikoerper
    Hintergrund

    Synonyms: POMT1_HUMAN, Protein O-mannosyl-transferase 1, Dolichyl-phosphate-mannose--protein mannosyltransferase 1.

    Background: POMT1 (Protein O mannosyl transferase 1) is a multipass membrane protein that is found in the endoplasmic reticulum. POMT1 catalyses the transfer of mannosyl residues to the hydroxyl groups of serine or threonine residues. Enzymatic activity is dependent on co expression of POMT1 with POMT2. Defects in the POMT1 gene are associated with Walker-Warburg syndrome (WWS), a congential muscular dystrophy that is associated with mental retardation and is usually lethal within the first few months of life. Other defects in the POMT1 gene result in limb girdle muscular dystrophy type 2K (LGMD2K), which is associated with mild mental retardation. Studies in Drosophila suggest that mutation of POMT1 alters the efficacy of synaptic transmission and a change in subunit composition of post synaptic glutamate receptors at the neuromuscular junction. Missense mutations in POMT1 have been associated with glioneuronal and glial brain tumours.

    Gen-ID
    10585
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