TBC1D1 Antikörper (C-Term)

Produktnummer ABIN500871

Produktdetails anti-TBC1D1 Antikörper

Target: TBC1D1 (TBC1 (Tre-2/USP6, BUB2, Cdc16) Domain Family, Member 1 (TBC1D1))

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TBC1D1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Spezifität: This antibody detects TBC1D1 at C-term.

Kreuzreaktivität (Details): Species reactivity (tested):Human

Aufreinigung: Peptide afiinity chromatography

Immunogen: TBC1D1 antibody was raised against a 22 amino acid peptide from near the carboxy terminus of human TBC1D1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA. Western blot.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS containing 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Details zu TBC1D1

Target: TBC1D1 (TBC1 (Tre-2/USP6, BUB2, Cdc16) Domain Family, Member 1 (TBC1D1))

Andere Bezeichnung: TBC1D1 (TBC1D1 Produkte)

Synonyme: TBC1D1 antikoerper, TBC antikoerper, TBC1 antikoerper, 1110062G02Rik antikoerper, AI385682 antikoerper, AW555803 antikoerper, Tbc1 antikoerper, mKIAA1108 antikoerper, TBC1 domain family member 1 antikoerper, TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1 antikoerper, TBC1 domain family, member 1 antikoerper, TBC1D1 antikoerper, tbc1d1 antikoerper, LOC100523386 antikoerper, Tbc1d1 antikoerper

Hintergrund: TBC1D1 is the founding member of a family of proteins sharing a 180- to 200-amino acid TBC domain and presumed to have a role in regulating cell growth and differentiation. These proteins share significant homology with TRE2/USP6, yeast Bub2, and CDC16. TBC1D1 and TBC1D4 (AS160) have been demonstrated to be Rab GAPs (GTPase-activating proteins) that link upstream to Akt and phosphoinositide 3-kinase and downstream to Rabs involved in trafficking of GLUT4 vesicles. TBC1D1 regulates insulin-mediated GLUT4 translocation through its GAP activity, and is a likely Akt substrate. Mutations in the Tbc1d1 gene lead to some cases of severe human obesity.Synonyms: KIAA1108, TBC1 domain family member 1

Gen-ID: 23216

NCBI Accession: NP_055988