OPRD1 Antikörper (pSer363) (Alexa Fluor 680)

Produktnummer ABIN5008025

Produktdetails anti-OPRD1 Antikörper (Alexa Fluor 680)

Target: OPRD1 (Opioid Receptor, delta 1 (OPRD1))

Bindungsspezifität: pSer363

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser OPRD1 Antikörper ist konjugiert mit Alexa Fluor 680

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Flow Cytometry (FACS)

Spezifität: This phosphorylation site is homologous in the listed cross reactive species at the specified location.

Kreuzreaktivität: Human, Maus, Ratte

Homologie: Cow,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human OPRD1 around the phosphorylation site of TP(p-S)DG

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu OPRD1

Target: OPRD1 (Opioid Receptor, delta 1 (OPRD1))

Andere Bezeichnung: OPRD1 (OPRD1 Produkte)

Synonyme: OPRD antikoerper, DOR-1 antikoerper, Nbor antikoerper, mDOR antikoerper, opioid receptor delta 1 antikoerper, opioid receptor, delta 1 antikoerper, OPRD1 antikoerper, Oprd1 antikoerper

Hintergrund:

Synonyms: OPRD, Delta-type opioid receptor, D-OR-1, DOR-1, OPRD1

Background: G-protein coupled receptor that functions as receptor for endogenous enkephalins and for a subset of other opioids. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling leads to the inhibition of adenylate cyclase activity. Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. Plays a role in the perception of pain and in opiate-mediated analgesia. Plays a role in developing analgesic tolerance to morphine.

Gen-ID: 4985

UniProt: P41143

Pathways: Protein targeting to Nucleus